Brewers vs. Cubs NLDS Game 5 Prediction, Odds, Picks - October 11

The Milwaukee Brewers will host the Chicago Cubs in the fifth and final game of the NLDS on Saturday at 8:08 p.m. ET, live on truTV, TBS, and HBO Max from American Family Field. The winner will advance to the NLCS after the teams split the first four games of the series. Oddsmakers list the Brewers as -140 favorites on the moneyline, while giving the underdog Cubs +119 moneyline odds. Milwaukee is a 1.5-run favorite (at +142 odds). A 7.5-run total is listed in the game.

Here's everything you need from a betting perspective on the Brewers-Cubs game, regarding the run line, moneyline and total, plus expert picks.

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Brewers vs. Cubs Game Information & Odds

• When: Saturday, October 11, 2025 at 8:08 p.m. ET
• Where: American Family Field in Milwaukee, Wisconsin
• How to watch on TV: truTV, TBS, and HBO Max

Brewers vs. Cubs Prediction

• Score Prediction: Brewers 5, Cubs 4
• Total Prediction: Over 7.5 runs
• Win Probabilities: Brewers 58%, Cubs 42%

Brewers vs. Cubs Betting Insights

• The Brewers have won 62, or 62%, of the 100 games they've played as favorites this season.
• This season Milwaukee has won 37 of its 49 games, or 75.5%, when favored by at least -140 on the moneyline.
• The bookmakers' moneyline implies a 58.3% chance of a victory for the Brewers.
• The Cubs have come away with 19 wins in the 49 contests they have been listed as the underdogs in this season.
• Chicago has a win-loss record of 5-10 when favored by +119 or worse by sportsbooks this year.
• The moneyline set for this matchup implies the Cubs have a 45.7% chance of walking away with the win.

Brewers Recent Betting Performance

• The Brewers have a 3-5 record across the eight games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups (all had set totals), the Brewers combined with their opponents to go over the run total five times.
• The Brewers' record against the spread is 4-6-0 over their past 10 games.

Brewers Recent Stats

Brewers Player Insights

• Brice Turang is the Brewers best hitter so far this season, hitting at a team-leading .288 rate along with 18 homers and 81 RBI.
• Of all hitters in baseball, Turang's home run total places him 105th, and his RBI tally puts him 52nd.
• Christian Yelich's 29 home runs and 103 runs batted in both lead his team.
• Yelich ranks 34th in home runs and 11th in RBI among all major league hitters this season.
• William Contreras is hitting .260 with 28 doubles, 17 home runs and 84 walks.
• Jackson Chourio has 35 doubles, four triples, 21 home runs and 30 walks while batting .270.
• Chourio is riding a six-game hitting streak into this one. In his last 10 games he is hitting .268 with three doubles, two home runs, two walks and seven RBIs.

Brewers Team Props

Cubs Recent Betting Performance

• In three games as underdogs over the last 10 matchups, the Cubs have a record of 1-2.
• The Cubs and their opponents have combined to hit the over five times in their last 10 games with a total.
• Over their last 10 games, the Cubs are 7-3-0 against the spread.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is batting .266 with 25 doubles, four triples, 22 home runs and 87 walks.
• Tucker is 65th in homers and 77th in RBI among all hitters in the big leagues.
• Nico Hoerner's .297 batting average leads his team.
• Hoerner is currently 264th in home runs and 123rd in RBI in the major leagues.
• Pete Crow-Armstrong is batting .247 with 37 doubles, four triples, 31 home runs and 29 walks.
• Michael Busch paces the Cubs with 34 home runs.

Cubs Team Props

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