Astros vs. White Sox Prediction, Odds, Picks - May 2

The Houston Astros and Isaac Paredes will square off against the Chicago White Sox and Andrew Benintendi at Rate Field on Friday, with the first pitch at 7:40 p.m. ET. The favored Astros have -239 moneyline odds against the underdog White Sox, who are listed at +196. Houston is a 1.5-run favorite (at -135 odds). The over/under for the game has been set at 8 runs.

Take a look at everything you need to know from a betting perspective on the Astros-White Sox game, regarding the run line, moneyline and total, plus expert picks.

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Brewers vs. White Sox Highlights | MLB on FOX

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Astros vs. White Sox Game Information & Odds

• When: Friday, May 2, 2025 at 7:40 p.m. ET
• Where: Rate Field in Chicago, Illinois
• How to watch on TV: CHSN and SCHN

Astros vs. White Sox Prediction

• Score Prediction: Astros 5, White Sox 4
• Total Prediction: Over 8 runs
• Win Probabilities: Astros 53%, White Sox 47%

Astros vs. White Sox Betting Insights

• This season, the Astros have been favored 21 times and won 11, or 52.4%, of those games.
• Houston has not entered a game this season as bigger favorites on the moneyline than the -239 odds on them winning this game.
• The Astros have a 70.5% chance to win this game based on the implied probability of the moneyline.
• The White Sox have been underdogs in 31 games this season and have come away with the win eight times (25.8%) in those contests.
• Chicago has a mark of 1-10 in contests where sportsbooks favor it by +196 or worse on the moneyline.
• The White Sox have an implied victory probability of 33.8% according to the moneyline set by oddsmakers for this matchup.

Astros Recent Betting Performance

• The Astros have a 5-4 record across the nine games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Astros and their opponents combined to go over the run total four times.
• The Astros have gone 7-3-0 against the spread over their past 10 games.

Astros Recent Stats

Astros Player Insights

• The Astros leader in both batting average and homers is Jeremy Pena, who comes into the contest hitting .282 and has left the yard four times while driving in 12 runs this season.
• Pena ranks 76th in homers and 128th in RBI among all hitters in the majors.
• Pena carries a five-game hitting streak into this matchup. During his last five outings he is batting .450 with two doubles, a home run, two walks and four RBI.
• Paredes has hit four home runs to pace his team.
• Paredes is 76th in homers and 90th in RBI in the bigs.
• Paredes carries a three-game streak with at least one hit into this contest. In his last five games he is batting .294 with a double, a triple, five walks and an RBI.
• Jose Altuve has launched a team-high four home runs.
• Yordan Alvarez has made the most of his opportunities as he leads his team with 18 RBI.
• Alvarez is riding a three-game hitting streak into this one. In his last five games he is batting .211 with a double, a home run, two walks and five RBI.

Astros Team Props

White Sox Recent Betting Performance

• The White Sox have played as underdogs in 10 of their past 10 games and won three of those contests.
• In their last 10 games with a total, the White Sox and their opponents have failed to hit the over five times.
• The White Sox have a record of 5-5-0 ATS over their last 10 games.

White Sox Recent Stats

White Sox Player Insights

• Luis Robert has put up a team-leading 13 runs batted in.
• Robert is 76th in homers and 107th in RBI among all hitters in the majors.
• Robert brings a hitting streak of six games into this matchup. During his last 10 games he is batting .231 with two doubles, two home runs, five walks and seven RBI.
• Benintendi has put up a team-high five home runs.
• Benintendi is 49th in home runs and 146th in RBI among all major league hitters this season.
• Miguel Vargas has six doubles, two home runs and 12 walks while hitting .222.
• Lenyn Sosa leads the team in batting average with a high-water mark of .269.

White Sox Team Props

Brewers vs. White Sox Highlights | MLB on FOX

Check out the best moments between the Milwaukee Brewers and the Chicago White Sox.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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