Astros vs. Angels Prediction, Odds, Picks - June 20

The Houston Astros and Los Angeles Angels will play on Friday at Angel Stadium, at 9:38 p.m. ET, with Jeremy Pena and Taylor Ward among those expected to deliver at the plate. The Astros are the favorite in this one, at -169, while the underdog Angels have +142 odds to play spoiler. Houston is the run-line favorite (-1.5). An 8-run total is set in this matchup.

Here's everything you need to know from a betting perspective on the Astros-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Check out the best moments between the Houston Astros and the Kansas City Royals.

Astros vs. Angels Game Information & Odds

• When: Friday, June 20, 2025 at 9:38 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and SCHN

Astros vs. Angels Prediction

• Score Prediction: Astros 6, Angels 5
• Total Prediction: Over 8 runs
• Win Probabilities: Astros 52%, Angels 48%

Astros vs. Angels Betting Insights

• The Astros have won 30, or 57.7%, of the 52 games they've played as favorites this season.
• Houston has entered 10 games this season favored by -169 or more and is 6-4 in those contests.
• The moneyline for this contest implies a 62.8% chance of a victory for the Astros.
• The Angels have been chosen as underdogs in 60 games this year and have walked away with the win 28 times (46.7%) in those games.
• This year, Los Angeles has won 11 of 23 games when listed as at least +142 or worse on the moneyline.
• The moneyline set for this matchup implies the Angels have a 41.3% chance of coming away with a victory in the contest.

Astros Recent Betting Performance

• The Astros went 5-3 over the eight games they were moneyline favorites in their last 10 matchups.
• In their last 10 matchups (all 10 of them had set totals), the Astros and their opponents combined to hit the over four times.
• The Astros' ATS record is 5-5-0 over their past 10 games.

Astros Recent Stats

Astros Player Insights

• Pena paces the Astros with a team-best batting average of .322.
• Pena ranks 83rd in home runs and 66th in RBI among all hitters in baseball.
• Pena has collected a hit in two straight games. During his last five outings he is batting .238 with two walks and three RBIs.
• Isaac Paredes has hit 15 home runs with 44 runs batted in. Both lead his team.
• Paredes ranks 15th in home runs and 27th in RBI in the major leagues.
• Jose Altuve has 10 doubles, 12 home runs and 20 walks while batting .273.
• Jake Meyers has 13 doubles, a triple, three home runs and 23 walks while batting .304.
• Meyers has recorded at least one hit in seven games in a row. In his last 10 games he is hitting .316 with two doubles, four walks and three RBIs.

Astros Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in seven of their past 10 games and won three of those contests.
• When it comes to hitting the over, the Angels and their opponents are 4-5-1 in their last 10 games with a total.
• The Angels have a record of 5-5-0 ATS over their last 10 games.

Angels Recent Stats

Angels Player Insights

• Nolan Schanuel leads the Angels with a team-high batting average of .278.
• Schanuel ranks 183rd in homers and 150th in RBI among all hitters in the big leagues.
• Ward has been a reliable source of runs this year, leading the lineup with 19 home runs and 50 RBI.
• Ward ranks ninth overall in home runs and 12th in RBI this year.
• Zach Neto has 13 doubles, a triple, 10 home runs and 11 walks while hitting .268.
• Jo Adell is hitting .221 with seven doubles, 15 home runs and 13 walks.

Angels Team Props

Astros vs. Royals Highlights | MLB on FOX

Check out the best moments between the Houston Astros and the Kansas City Royals.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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