Angels vs. Twins Prediction, Odds, Picks - September 10

Jo Adell and the Los Angeles Angels take the field against Trevor Larnach and the Minnesota Twins on Wednesday at 4:07 p.m. ET, in the final of a three-game series at Angel Stadium. The Twins have been listed as +114 moneyline underdogs in this matchup with the favored Angels (-135). Los Angeles is favored on the run line (-1.5). The total is 9 runs for this matchup (with -105 odds to hit the over and -115 odds to go under).

Here is everything you need to know from a betting perspective on the Angels-Twins game, regarding the run line, moneyline and total, plus expert picks.

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Angels vs. Twins Game Information & Odds

• When: Wednesday, September 10, 2025 at 4:07 p.m. ET
• Where: Angel Stadium in Anaheim, California
• How to watch on TV: FDSW and MNNT

Angels vs. Twins Prediction

• Score Prediction: Angels 6, Twins 5
• Total Prediction: Over 9 runs
• Win Probabilities: Angels 52%, Twins 48%

Angels vs. Twins Betting Insights

• This season, the Angels have been favored 36 times and won 17, or 47.2%, of those games.
• Los Angeles has a record of 8-7, a 53.3% win rate, when favored by -135 or more by sportsbooks this season.
• Oddsmakers have implied with the moneyline set for this matchup that the Angels have a 57.4% chance to win.
• The Twins have been victorious in 23, or 39.7%, of the 58 contests they have been chosen as underdogs in this season.
• Minnesota has a mark of 9-15 in contests where oddsmakers favor it by +114 or worse on the moneyline.
• The Twins have an implied victory probability of 46.7% according to the moneyline set for this matchup.

Angels Recent Betting Performance

• The Angels were the moneyline favorite three times in the last 10 games, but they lost every matchup.
• In their last 10 outings, the Angels and their opponents combined to go over the run total five times (all 10 games had set totals).
• The Angels' ATS record is 6-4-0 over their past 10 games.

Angels Recent Stats

Angels Player Insights

• Taylor Ward has sent home a team-high 96 runs batted in.
• Of all hitters in MLB, Ward's home run total ranks him 12th, and his RBI tally ranks him 10th.
• Adell has hit 35 home runs to lead his team.
• Adell is eighth in homers in MLB, and 11th in RBI.
• Adell has two straight games with at least one hit. During his last five outings he is batting .316 with three home runs, two walks and eight RBIs.
• Zach Neto is hitting .257 with 29 doubles, a triple, 25 home runs and 32 walks.
• Neto will look to build on his two-game hitting in this matchup. In his last five games he is hitting .133 with a walk.
• Mike Trout is batting .233 with 13 doubles, a triple, 20 home runs and 82 walks.
• Trout is riding a four-game hitting streak into this one. During his last five outings he is hitting .294 with a double, five walks and an RBI.

Angels Team Props

Twins Recent Betting Performance

• In three games as underdogs over the last 10 matchups, the Twins have a record of 2-1.
• When it comes to hitting the over, the Twins and their opponents are 7-3-0 in their last 10 games with a total.
• The Twins have a record of 4-6-0 ATS over their last 10 games.

Twins Recent Stats

Twins Player Insights

• Byron Buxton leads the Twins in home runs (30), runs batted in (74) and has put up a team-best batting average of .274.
• Buxton's home run total places him 12th in MLB, and he ranks 48th in RBI.
• Buxton carries a three-game hitting streak into this matchup. During his last five outings he is hitting .333 with a double, two triples, a home run and two RBIs.
• Larnach is hitting .254 with 20 doubles, a triple, 16 home runs and 47 walks.
• Larnach is 109th in home runs and 110th in RBI among all major league batters this season.
• Brooks Lee is hitting .239 with 14 doubles, a triple, 14 home runs and 28 walks.
• Royce Lewis is hitting .234 with 16 doubles, 12 home runs and 25 walks.

Twins Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Los Angeles Angels

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