San Diego State vs. San Jose State Prediction, Odds, Picks - November 22, 2025

Updated Nov. 22, 2025 9:04 p.m. ET

Data Skrive

The San Diego State Aztecs (8-2) bring the ninth-ranked passing defense in college football into a matchup with the San Jose State Spartans (3-7), who have the No. 3 passing offense, on Saturday, November 22, 2025. The Aztecs are heavy, 11.5-point favorites. The over/under for the game is set at 50.5.

In their last action, the Aztecs won versus the Boise State Broncos, 17-7. In their most recent game, the Spartans lost against the Nevada Wolf Pack, 55-10.

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San Diego State vs. San Jose State Game Information & Odds

When: Saturday, November 22, 2025 at 10:30 p.m. ET
Location: Snapdragon Stadium in San Diego, California
TV: FS1
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

San Diego State vs San Jose State Betting Information updated as of November 22, 2025, 12:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
San Diego State	-11.5 (-112)	-498	+373	50.5	-109	-111

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San Diego State vs. San Jose State Prediction

Pick ATS: San Diego State (-11.5)
Pick OU: Under (50.5)
Prediction: San Diego State 35, San Jose State 12

Predictions are made by the Data Skrive betting model.

Learn more about the San Diego State Aztecs vs. the San Jose State Spartans game on FOX Sports!

San Diego State vs. San Jose State Betting Insights

Based on the spread and over/under, the implied score for the tilt is Aztecs 31, Spartans 20.
The Aztecs have an 83.3% chance to collect the win in this contest based on the moneyline's implied probability. The Spartans hold a 21.1% implied probability.
San Diego State has compiled an 8-2-0 ATS record so far this year.
San Jose State is 4-6-0 ATS this year.

San Diego State vs. San Jose State: Head-to-Head

San Diego State has a 2-1 record against San Jose State in their last three matchups.
The Aztecs carry a 2-1 record ATS in those games, while the two teams have gone over the point total on one occasion.
In their last three head-to-head matchups, San Diego State has scored 75 points against San Jose State, while allowing only 64 points.

San Diego State vs. San Jose State: 2025 Stats Comparison

	San Diego State	San Jose State
Off. Points per Game (Rank)	25.4 (95)	24 (106)
Def. Points per Game (Rank)	12.5 (2)	32.4 (111)
Turnovers Allowed (Rank)	10 (21)	20 (123)
Turnovers Forced (Rank)	13 (63)	11 (93)

San Diego State 2025 Key Players

Name	Position	Stats
Lucky Sutton	RB	1,043 YDS / 8 TD / 104.3 YPG / 5.3 YPC
Jayden Denegal	QB	1,567 YDS (59.3%) / 8 TD / 7 INT 99 RUSH YDS / 3 RUSH TD / 9.9 RUSH YPG
Jordan Napier	WR	48 REC / 632 YDS / 2 TD / 63.2 YPG
Christian Washington	RB	336 YDS / 2 TD / 33.6 YPG / 5.1 YPC 3 REC / 18 REC YDS / 1 REC TD / 6 REC YPG
Owen Chambliss	LB	74 TKL / 8 TFL / 4 SACK / 1 INT
Trey White	DL	34 TKL / 6 TFL / 6 SACK
Chris Johnson	DB	41 TKL / 2 TFL / 3 INT / 3 PD
Dalesean Staley	DB	45 TKL / 0 TFL / 1 INT / 1 PD

San Jose State 2025 Key Players

Name	Position	Stats
Walker Eget	QB	3,026 YDS (59.2%) / 17 TD / 8 INT
Danny Scudero	WR	72 REC / 1,161 YDS / 10 TD / 116.1 YPG
Leland Smith	WR	39 REC / 661 YDS / 3 TD / 66.1 YPG
Kyri Shoels	WR	55 REC / 727 YDS / 2 TD / 72.7 YPG
Jordan Pollard	LB	65 TKL / 2 TFL / 2.5 SACK
Taniela Latu	LB	43 TKL / 2 TFL / 1 SACK / 1 INT
Jalen Bainer	DB	30 TKL / 1 TFL / 1 SACK / 3 INT
Vili Taufatofua	DL	24 TKL / 3 TFL / 4 SACK