Ohio State vs. Illinois Prediction, Odds, Picks - October 11, 2025
Updated Oct. 11, 2025 9:04 a.m. ET
Data Skrive
The No. 1 Ohio State Buckeyes (5-0) will put their first-ranked scoring defense to the test against the No. 17 Illinois Fighting Illini (5-1) and the No. 25 scoring offense in college football, on Saturday, October 11, 2025. The Buckeyes are heavily favored by 14.5 points in the game. This game has an over/under of 50.5 points.
In their last game, the Buckeyes won against the Minnesota Golden Gophers, 42-3. The Fighting Illini beat the Purdue Boilermakers, 43-27, in their most recent contest.
Keep up with college football all season on FOX Sports.
Ohio State vs. Illinois Game Information & Odds
- When: Saturday, October 11, 2025 at 12 p.m. ET
- Location: Memorial Stadium (Champaign, IL) in Champaign, Illinois
- TV: FOX
- Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
| Favorite | Spread (Odds) | Favorite Moneyline | Underdog Moneyline | Total | Over Moneyline | Under Moneyline |
|---|---|---|---|---|---|---|
| Ohio State | -14.5 (-111) | -699 | +500 | 50.5 | -111 | -109 |
Ohio State vs. Illinois Prediction
- Pick ATS: Illinois (+14.5)
- Pick OU: Under (50.5)
- Prediction: Illinois 26, Ohio State 23
Predictions are made by the Data Skrive betting model.
Learn more about the Ohio State Buckeyes vs. the Illinois Fighting Illini game on FOX Sports!
Ohio State vs. Illinois Betting Insights
- Per the spread and over/under, the implied score for the game is Buckeyes 32, Fighting Illini 18.
- The Buckeyes have an 87.5% chance to collect the win in this game per the moneyline's implied probability. The Fighting Illini hold a 16.7% implied probability.
- Ohio State has put together a 4-1-0 record against the spread this season.
- Illinois has won five games against the spread this year, failing to cover once.
Ohio State vs. Illinois: 2025 Stats Comparison
| Ohio State | Illinois | |
|---|---|---|
| Off. Points per Game (Rank) | 37.4 (34) | 37 (14) |
| Def. Points per Game (Rank) | 5 (1) | 24 (84) |
| Turnovers Allowed (Rank) | 4 (18) | 3 (9) |
| Turnovers Forced (Rank) | 4 (106) | 10 (15) |
Ohio State 2025 Key Players
| Name | Position | Stats |
|---|---|---|
| Julian Sayin | QB | 1,313 YDS (80.2%) / 13 TD / 3 INT |
| Jeremiah Smith | WR | 35 REC / 463 YDS / 6 TD / 92.6 YPG |
| Carnell Tate | WR | 24 REC / 435 YDS / 4 TD / 87 YPG |
| CJ Donaldson | RB | 193 YDS / 4 TD / 38.6 YPG / 4.3 YPC 4 REC / 26 REC YDS / 1 REC TD / 8.7 REC YPG |
| Caden Curry | DL | 28 TKL / 8 TFL / 5 SACK |
| Kayden McDonald | DL | 23 TKL / 5 TFL / 3 SACK |
| Arvell Reese | LB | 29 TKL / 3 TFL / 3 SACK |
| Sonny Styles | LB | 29 TKL / 1 TFL |
Illinois 2025 Key Players
| Name | Position | Stats |
|---|---|---|
| Luke Altmyer | QB | 1,573 YDS (73.6%) / 12 TD / 0 INT -8 RUSH YDS / 2 RUSH TD / -1.3 RUSH YPG |
| Hank Beatty | WR | 32 REC / 569 YDS / 2 TD / 94.8 YPG |
| Kaden Feagin | RB | 316 YDS / 5 TD / 52.7 YPG / 4 YPC 8 REC / 100 REC YDS / 1 REC TD / 25 REC YPG |
| Ca'Lil Valentine | RB | 323 YDS / 3 TD / 53.8 YPG / 5.3 YPC |
| Gabe Jacas | LB | 16 TKL / 1 TFL / 4.5 SACK |
| Matthew Bailey | DB | 26 TKL / 0 TFL |
| Dylan Rosiek | LB | 19 TKL / 2 TFL / 1 INT / 1 PD |
| Leon Lowery | LB | 13 TKL / 3 TFL / 2 SACK |
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
Want great stories delivered right to your inbox?
FOLLOW Follow your favorites to personalize your FOX Sports experience
share
recommended
How to Watch NASCAR at Las Vegas: TV Channel, Streaming, Time
2026 NCAA Tournament Projections: Florida Still a No. 1 Seed? Miami (OH) In or Out?
2026 World Baseball Classic Bracket, Schedule, Standings
4 Takeaways From Inaugural Arlington Race: Kyle Kirkwood Wins With Big-Time Move
2026 NCAA Men’s Tournament: 5 Biggest March Madness Snubs
Everything To Know For Inaugural INDYCAR Race Around Cowboys' Stadium, Including New Time
Selection Sunday: How to Watch March Madness Men's Bracket Reveal
Jerry Jones Compares Pato O'Ward's 'Controlled Intensity' to Deion Sanders' Approach
2026 World Baseball Classic Broadcast Schedule: How To Watch Every Game on FOX
Item 1 of 3
recommended
-
How to Watch NASCAR at Las Vegas: TV Channel, Streaming, Time
2026 NCAA Tournament Projections: Florida Still a No. 1 Seed? Miami (OH) In or Out?
2026 World Baseball Classic Bracket, Schedule, Standings
-
4 Takeaways From Inaugural Arlington Race: Kyle Kirkwood Wins With Big-Time Move
2026 NCAA Men’s Tournament: 5 Biggest March Madness Snubs
Everything To Know For Inaugural INDYCAR Race Around Cowboys' Stadium, Including New Time
-
Selection Sunday: How to Watch March Madness Men's Bracket Reveal
Jerry Jones Compares Pato O'Ward's 'Controlled Intensity' to Deion Sanders' Approach
2026 World Baseball Classic Broadcast Schedule: How To Watch Every Game on FOX
Item 1 of 3
