Middle Tennessee vs. Sam Houston Prediction, Odds, Picks - November 22, 2025

Updated Nov. 22, 2025 3:05 p.m. ET

Data Skrive

The Middle Tennessee Blue Raiders (1-9) are 6.5-point favorites when they host the Sam Houston Bearkats (2-8) in a CUSA matchup on Saturday, November 22, 2025 at Johnny "Red" Floyd Stadium. The over/under for the contest is set at 53.5.

The Blue Raiders' most recent contest was versus the Western Kentucky Hilltoppers, and they lost by a score of 42-26. The Bearkats beat the Delaware Blue Hens, 26-23, in their last contest.

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Middle Tennessee vs. Sam Houston Game Information & Odds

When: Saturday, November 22, 2025 at 3 p.m. ET
Location: Johnny "Red" Floyd Stadium in Murfreesboro, Tennessee
TV: ESPN+
Live Box Score on FOX Sports

Middle Tennessee vs Sam Houston Betting Information updated as of November 22, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Middle Tennessee	-6.5 (-116)	-246	+200	53.5	-110	-110

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Middle Tennessee vs. Sam Houston Prediction

Pick ATS: Sam Houston (+6.5)
Pick OU: Over (53.5)
Prediction: Middle Tennessee 29, Sam Houston 25

Predictions are made by the Data Skrive betting model.

Learn more about the Middle Tennessee Blue Raiders vs. the Sam Houston Bearkats game on FOX Sports!

Middle Tennessee vs. Sam Houston Betting Insights

Based on the spread and over/under, the implied score for the game is Blue Raiders 30, Bearkats 24.
The Blue Raiders have a 71.1% chance to collect the win in this contest based on the moneyline's implied probability. The Bearkats have a 33.3% implied probability.
Middle Tennessee is 4-6-0 ATS this season.
Sam Houston is 3-7-0 ATS this season.

Middle Tennessee vs. Sam Houston: 2025 Stats Comparison

	Middle Tennessee	Sam Houston
Off. Points per Game (Rank)	20.7 (117)	18 (126)
Def. Points per Game (Rank)	33 (125)	36.7 (130)
Turnovers Allowed (Rank)	12 (54)	11 (43)
Turnovers Forced (Rank)	11 (87)	17 (25)

Middle Tennessee 2025 Key Players

Name	Position	Stats
Nicholas Vattiato	QB	2,157 YDS (61.3%) / 16 TD / 7 INT 20 RUSH YDS / 2 RUSH TD / 2.2 RUSH YPG
Jekail Middlebrook	RB	551 YDS / 4 TD / 61.2 YPG / 5.2 YPC 37 REC / 369 REC YDS / 2 REC TD / 41 REC YPG
Nahzae Cox	WR	38 REC / 446 YDS / 5 TD / 49.6 YPG
Cam'ron Lacy	WR	35 REC / 499 YDS / 3 TD / 62.4 YPG
Parker Hughes	LB	41 TKL / 1 TFL / 1 INT / 1 PD
Brandon Buckner	LB	20 TKL / 4 TFL / 4.5 SACK
Damonte Smith	DL	18 TKL / 4 TFL / 2 SACK / 1 INT
Reggie Johnson	LB	16 TKL / 5 TFL / 3.5 SACK

Sam Houston 2025 Key Players

Name	Position	Stats
Hunter Watson	QB	1,108 YDS (57.1%) / 5 TD / 4 INT 276 RUSH YDS / 2 RUSH TD / 39.4 RUSH YPG
Landan Brown	RB	415 YDS / 4 TD / 46.1 YPG / 6 YPC 31 REC / 180 REC YDS / 0 REC TD / 20 REC YPG
Elijah Green	RB	293 YDS / 2 TD / 41.9 YPG / 6.2 YPC 14 REC / 136 REC YDS / 1 REC TD / 19.4 REC YPG
Chris Reed	WR	22 REC / 344 YDS / 3 TD / 34.4 YPG
Antavious Fish	LB	45 TKL / 2 TFL / 1 SACK
Christopher Eaton Jr.	DL	15 TKL / 6 TFL / 5 SACK
Emon Allen	DB	25 TKL / 2 TFL / 3 INT / 3 PD
Cecil Powell	DB	28 TKL / 1 TFL / 1 INT / 1 PD