Penn State vs. Pittsburgh Prediction, How to Watch, Odds, Channel - Dec 21

Published Dec. 20, 2025 3:27 p.m. ET

Data Skrive

The Penn State Nittany Lions (8-3) go up against the Pittsburgh Panthers (6-6) on Sunday, December 21, 2025 at 12 p.m. ET. The matchup airs on Big Ten Network.

The Nittany Lions face the Panthers in a game projected to be a hard-fought meeting. The Nittany Lions are favored by only 1.5 points against the Panthers. The matchup features an over/under of 149.5.

Keep scrolling to get everything you need to know ahead of wagering on the Penn State-Pittsburgh contest.

Penn State vs. Pittsburgh How to Watch & Odds

When: Sunday, December 21, 2025 at 12 p.m. ET
Where: GIANT Center in Hershey, Pennsylvania
TV: Big Ten Network
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Nittany Lions vs Panthers Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Nittany Lions	-1.5	-102	-120	149.5	-110	-110	-115	-104

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Penn State vs. Pittsburgh Prediction

Pick ATS: Pittsburgh (+1.5)
Pick OU: Under (149.5)
Prediction: Penn State 75, Pittsburgh 74

Learn more about the Penn State Nittany Lions vs. the Pittsburgh Panthers game on FOX Sports!

Penn State vs. Pittsburgh Betting Insights

Betting Line Implied Predictions

Based on the spread and over/under, the implied score for the encounter is Nittany Lions 76, Panthers 74.
The Nittany Lions have a 53.5% chance to collect the win in this meeting based on the moneyline's implied probability.
The Panthers sit with a 51.0% implied probability to win.

Key Spread Facts

Penn State has compiled a 4-7-0 record against the spread this season.
Pittsburgh has compiled a 5-7-0 ATS record so far this year.
When playing as at least 1.5-point favorites this season, Penn State has an ATS record of 3-5.
Pittsburgh has covered the spread once when an underdog by 1.5 points or more this year (in four opportunities).

Key Total Facts

The Nittany Lions and their opponent have broken the 149.5-point mark six times this season.
There have been four Panthers games this season with more than 149.5 points scored.
These two teams score a combined average of 154.6 points per game, higher than the total for this matchup by 5.1 points.

Key Moneyline Facts

Penn State has won all eight games when listed as the moneyline favorite this season.
This season, Pittsburgh has won one out of the four games in which it has been the underdog.
Penn State has won all eight games it played as a moneyline favorite with odds of -115 or shorter.
Pittsburgh has a record of 1-3 when it is set as the underdog by -104 or more by oddsmakers this season.

Penn State vs. Pittsburgh: 2025-26 Stats Comparison

	Penn State	Pittsburgh
Points Scored Per Game (Rank)	81.1 (110)	73.5 (274)
Points Allowed (Rank)	74.5 (216)	69.6 (97)
Rebounds (Rank)	8.3 (288)	10.4 (117)
3pt Made (Rank)	7.1 (262)	8.5 (133)
Assists (Rank)	14.1 (213)	13.2 (267)
Turnovers (Rank)	8.7 (6)	11.3 (152)

Penn State 2025-26 Key Players

Nittany Lions Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Kayden Mingo	11	15.0	4.1	4.4	2.1	0.1	0.6
Freddie Filione V	11	14.2	3.4	2.4	1.3	0.1	1.4
Melih Tunca	11	12.1	2.7	3.2	0.9	0.4	1.1
Ivan Jurić	11	9.7	4.1	0.5	0.3	0.3	0.5
Josh Reed	11	9.5	4.1	1.0	1.2	0.1	0.5

Pittsburgh 2025-26 Key Players

Panthers Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Cameron Corhen	12	13.5	8.7	1.9	0.9	0.8	0.5
Brandin Cummings	9	13.2	1.2	2.2	0.7	0.1	1.9
Barry Dunning Jr.	12	12.8	4.9	0.7	0.5	1.3	2.0
Damarco Minor	12	10.4	4.0	3.3	1.5	0.3	1.8
Nojus Indrusaitis	12	9.7	3.1	1.7	0.9	0.2	1.6