Ohio State vs. Pittsburgh Prediction, How to Watch, Odds, Channel - Nov 28

Updated Nov. 28, 2025 8:27 p.m. ET

Data Skrive

The Ohio State Buckeyes (6-0) will attempt to continue a six-game win streak when they visit the Pittsburgh Panthers (4-3) on Friday, November 28, 2025 at Petersen Events Center. The contest airs at 7 p.m. ET on ESPN2.

The Buckeyes are a 5.5-point favorite against the Panthers when the Buckeyes and the Panthers meet. The point total for the matchup is 148.5.

Keep reading to get the details before wagering on the Ohio State-Pittsburgh game.

Ohio State vs. Pittsburgh How to Watch & Odds

When: Friday, November 28, 2025 at 7 p.m. ET
Where: Petersen Events Center in Pittsburgh, Pennsylvania
TV: ESPN2
Live Box Score: FOX Sports

Buckeyes vs Panthers Betting Information
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds	Favorite Moneyline	Underdog Moneyline
Buckeyes	-5.5	-110	-110	148.5	-112	-108	-244	+199

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Ohio State vs. Pittsburgh Prediction

Pick ATS: Ohio State (-5.5)
Pick OU: Over (148.5)
Prediction: Ohio State 78, Pittsburgh 71

Learn more about the Ohio State Buckeyes vs. the Pittsburgh Panthers game on FOX Sports!

Ohio State vs. Pittsburgh Betting Insights

Betting Line Implied Predictions

Based on the spread and over/under, the implied score for the game is Buckeyes 77, Panthers 72.
The Buckeyes have a 70.9% chance to claim victory in this matchup based on the moneyline's implied probability.
The Panthers sit with a 33.4% implied probability to win.

Key Spread Facts

Ohio State has won three games against the spread this season, while failing to cover three times.
Pittsburgh has covered three times in seven games with a spread this season.
Ohio State has an ATS record of 3-3 when playing as at least 5.5-point favorites this season.
Pittsburgh has been an underdog by 5.5 points or more this season once, and failed to cover the spread.

Key Total Facts

The Buckeyes and their opponent have broken the 148.5-point mark four times this season.
Panthers games have finished with over 148.5 points just one time this year.
The Buckeyes and Panthers combine to average 164.6 points per contest, which is 16.1 more than the total for this game.

Key Moneyline Facts

Ohio State has been favored on the moneyline a total of six times this season, and it has won all of those games.
Pittsburgh lost the only game it has played as the underdog this season.
Ohio State has won all six games it played as a moneyline favorite with odds of -244 or shorter.
Pittsburgh has played as an underdog of +199 or more once this season and lost that game.

Ohio State vs. Pittsburgh: Recent Results

Buckeyes vs Panthers Recent Games
Date	Favorite	Spread	Total	Favorite Moneyline	Underdog Moneyline	Result
11/29/2024	Buckeyes	-3.5	147	-165	+138	91-90 PITT

Ohio State vs. Pittsburgh: 2025-26 Stats Comparison

	Ohio State	Pittsburgh
Points Scored Per Game (Rank)	92.5 (20)	72.1 (289)
Points Allowed (Rank)	67.3 (70)	66.6 (61)
Rebounds (Rank)	7.7 (324)	11 (86)
3pt Made (Rank)	10.3 (46)	8.3 (153)
Assists (Rank)	17.5 (51)	13.3 (245)
Turnovers (Rank)	11 (120)	12.6 (225)

Ohio State 2025-26 Key Players

Buckeyes Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Bruce Thornton	6	21	4	3.5	1.3	0.2	3
John Mobley Jr.	6	16.8	2.5	3.3	0.5	0	2.8
Christoph Tilly	6	16.5	5.2	3.5	0.5	0.7	0.7
Devin Royal	5	12.4	6	1.4	1	0	1.4
A'mare Bynum	6	7.8	4	1	0.2	0	0.7

Pittsburgh 2025-26 Key Players

Panthers Leaders
Name	GP	PTS	REB	ASST	STL	BLK	3PM
Cameron Corhen	7	14	9.6	2	1	1.3	0.6
Brandin Cummings	5	12.4	1.2	1.4	0.8	0	1.8
Damarco Minor	7	10.4	4.9	3.4	1.3	0.3	1.7
Nojus Indrusaitis	7	9.4	3.1	1.6	0.7	0.1	1.6
Barry Dunning Jr.	7	9.3	4	0.6	0.3	1	1.9