Dwight Thorne had 19 points, leading five Colorado players in double figures, and the Buffaloes scored a season high in routing Cal State Northridge 92-58 Tuesday night.
Alec Burks and Cory Higgins added 14 points each for Colorado (7-4), which improved to 6-0 at home - its best season-opening run since starting 7-0 at the Coors Events Center in 2005-06.
Northridge (4-7), which has lost all five of its road games this season, was led by Vinnie McGhee with 13 points and Mark Hill with 12.
Colorado outshot Northridge 56.1 percent to 32.7 percent from the field and made 10 of its 25 3-point attempts, one shy of its season high.
The Buffaloes hit seven 3-pointers in the opening 20 minutes, helping them take a 41-21 halftime lead. During one seven-minute sequence, four Colorado players hit five 3-pointers in a row as the Buffaloes stretched their lead from 8-3 to 23-10.