Alvaro Odriozola, who started for Spain at right back for the injured Dani Carvajal, misjudged a pass by Thiago Alcantara in the 13th minute to gift Tunisia its best opportunity. Ferjani Sassi, however, shot weakly into the arms of David de Gea.
The African side went close again after attacking again down Odriozola’s side after robbing the ball from Busquets, only for Naim Sliti to fail to make contact with a cross with only de Gea to beat.
Lopetegui made three changes at halftime, sending on Jorge ”Koke” Resurreccion and Lucas Vazquez for Thiago and Francisco ”Isco” Alarcon, and Nacho Fernandez for Odriozola.
Moments after Silva volleyed a shot from a tight angle past the post, the midfielder was replaced by Marco Asensio, while Costa substituted Rodrigo Moreno with half an hour remaining.
With Spain not improving, Lopetegui sent on striker Aspas for Jordi Alba and switched to a three-man defense.