NFL > Scores >

Jacksonville Jaguars vs. San Francisco 49ers - News: Sep 28, 2025

3-1
26
FINAL
21
3-1
49ers
3-1
Dee Winters - Estimated as limited Winters was listed as a limited participant in Monday's estimated practice report due to a knee injury.
Impact Winters played every single defensive snap during the 49ers' 26-21 loss to the Jaguars on Sunday and finished with 10 tackles (nine solo) and one pass defense. He's come out of that contest with a knee injury, which will be worth monitoring given the 49ers are playing on short rest against the Rams on Thursday.
SEPTEMBER 29, 2025 • ROTOWIRE
Sean McVay talks about Rams' defense neutralizing opposing offenses' run game, impressions of the 49ers & more Los Angeles Rams head coach Sean McVay talks about the Rams' defense neutralizing the run game, his impression so far regarding the San Fran...
SEPTEMBER 29, 2025 • THERAMS.COM
First Look: Rams host 49ers on Thursday Night Football in Week 5 An early preview of Thursday Night Football between the Rams and the 49ers at SoFi Stadium in Week 5.
SEPTEMBER 29, 2025 • THERAMS.COM
Liam Coen Talks Key Contributors & Game Plan in Week 4 Win | Press Conference Jaguars HC Liam Coen speaks to the media on Monday of Week 5 during the 2025 NFL Season.
SEPTEMBER 29, 2025 • JAGUARS.COM
Trevor Lawrence issues warning after 49ers win that should concern Patrick Mahomes and the Chiefs After defeating the San Francisco 49ers, Trevor Lawrence revealed the Jaguars’ state of mind—something that should concern Patrick Mahomes,...
SEPTEMBER 29, 2025 • BOLAVIP.COM
Mac Jones - Listed as full Monday Jones (knee) was listed as a full participant on Monday's practice estimate.
Impact Jones was limited all of last week due to a PCL sprain that he suffered in Week 3 against the Cardinals, but he was able to handle backup duties Sunday versus the Jaguars with Brock Purdy (left shoulder/toe) back in action. Purdy emerged from that contest with toe soreness and was listed as a DNP on Monday. Considering Jones now has a clean bill of health and Purdy doesn't as the 49ers prepare for Thursday's contest at the Rams, Jones may be called upon to make his third start of the year in Week 5.
SEPTEMBER 29, 2025 • ROTOWIRE
Mac Jones - Listed as full Monday Jones (knee) was listed as full on Monday's practice estimate.
Impact Jones was limited all of last week due to a PCL sprain that he suffered Week 3 against the Cardinals, but he was able to handle backup duties Sunday versus the Jaguars with Brock Purdy (left shoulder/toe) back in action. Purdy emerged from the latter contest with toe soreness and was listed as a DNP on Monday, with coach Kyle Shanahan telling David Lombardi of SFStandard.com that Purdy will be evaluated. Considering Jones now has a clean bill of health and Purdy doesn't as the 49ers prepare for Thursday's contest at the Rams, Jones may be called upon to start again Week 5 as he did Weeks 2 and 3 if Purdy isn't cleared for game action.
SEPTEMBER 29, 2025 • ROTOWIRE

FOX FACTS

2
MILESTONE
Fred Warner has passed Patrick Willis for sole possession of 1st on the 49ers all-time fumbles forced list with 17.
MILESTONE
Travis Etienne Jr. has passed Stacey Mack for sole possession of 4th on the Jaguars all-time rushing touchdowns list with 20.
Follow your favorite leagues, teams and players to personalize your FOX Sports experience.
Jacksonville Jaguars
Jacksonville Jaguars
San Francisco 49ers
San Francisco 49ers

EVENT INFO

Levi's Stadium
Levi's Stadium
Santa Clara, CA
Sep 28, 2025
70,495
3 Hours 8 Minutes