ISAAC GUERENDO NEWS

In line for RB1 duties With Christian McCaffrey (knee) and Jordan Mason (ankle) in line to be placed on injured reserve, Guerendo is expected to take over as the 49ers' starting running back, Adam Scheft...

Impact McCaffrey will miss at least the remainder of the regular season with his sprained PCL, and Mason is dealing with a high-ankle sprain. The injuries vault Guerendo to the top of the depth chart. The rookie has seen limited work as a rookie this season, but he's averaged a crisp 5.9 yards per carry on his 42 totes, turning them into 246 yards and two touchdowns. He's added five catches for 19 yards on six targets. Guerendo is a size-speed specimen at 6-foot and 221 pounds with a 4.33 forty-yard dash time. He will be the top waiver-wire priority in fantasy leagues this week.

DECEMBER 2, 2024 • ROTOWIRE

49ers' Christian McCaffrey to be placed on IR after suffering PCL injury

49ers running back Christian McCaffrey's season might be over as he, along with backup running back Jordan Mason, will be placed on injured...

DECEMBER 2, 2024

Rips off 15-yard touchdown Guerendo took four carries for 19 yards and a touchdown while losing three yards on his only reception in Sunday's 35-10 loss to the Bills.

Impact Guerendo got some extra run in the second half after starter Christian McCaffrey (knee) left the game due to injury at halftime. Jordan Mason (13-78-0) took over as the primary rusher from there on out, but Guerendo benefited from scoring the 49ers' only offensive touchdown in the blowout loss. Mason is the name to grab on waivers this week, but he showed some durability issues handling the starter's role earlier this season in addition to being evaluated for a concussion against Buffalo. Guerendo is more of a stash option for next Sunday's tilt against the Bears, but he carries some appeal for those in deeper leagues with CMC likely done for the year.

DECEMBER 2, 2024 • ROTOWIRE

Isaac Guerendo Could Be Most Valuable Fantasy Football Asset Over Jordan Mason With Christian McCaffrey Injured Isaac Guerendo and Jordan Mason are both top waiver wire adds this week with Christian McCaffrey hurt.

DECEMBER 2, 2024 • NEWSOBSERVER.COM

Isaac Guerendo Races to the Pylon for a 15-Yard Touchdown San Francisco 49ers RB Isaac Guerendo sped past the Buffalo Bills defense for a touchdown on "SNF".

DECEMBER 2, 2024 • 49ERS.COM

Resumes No. 3 role Guerendo had one carry for zero yards in Sunday's 23-20 win over Tampa Bay.

Impact With star tailback Christian McCaffrey (Achilles) returning to action and backup Jordan Mason (shoulder) healthy, Guerendo was relegated to third on San Francisco's depth chart. The rookie logged just three snaps on offense (five percent) while taking his only touch for no gain. Guerendo produced a pair of strong fantasy performances in the weeks covering for his injured teammates, but managers can safely move on from the Louisville product in such a reduced role.

NOVEMBER 11, 2024 • ROTOWIRE

Isaac Guerendo Nominated for Pepsi Zero Sugar Rookie of the Week Award - Week 8 San Francisco 49ers running back Isaac Guerendo was nominated for the Pepsi Zero Sugar Rookie of the Week Award after closing out Week 8 as...

OCTOBER 29, 2024 • 49ERS.COM

Isaac Guerendo's Best Plays vs. Dallas Cowboys in Week 8 Watch all of San Francisco 49ers rookie running back Isaac Guerendo's best plays from his 102-yard game against the Dallas Cowboys in Week 8...

OCTOBER 28, 2024 • 49ERS.COM

Steps in for injured starter again Guerendo rushed 14 times for 85 yards and a touchdown while securing three of four targets for 17 yards in Sunday's 30-24 win over Dallas.

Impact Guerendo was elevated to starter mid-game after Jordan Mason (shoulder) aggravated a nagging AC joint injury early in the contest. The 24-year-old Guerendo performed as he did the last time this scenario unfolded, which is one of the reason's the rookie was pegged a deep sleeper heading into drafts this year. The downside from a fantasy perspective is that San Francisco will observe its bye this upcoming week, and star running back Christian McCaffrey (Achilles) has a shot at returning in Week 10 against Tampa Bay. Guerendo still is worth looking at if he was dropped prior to Mason's activation Sunday, but be aware of CMC's status come Nov. 10.

OCTOBER 28, 2024 • ROTOWIRE

Steps in for injured starter again Guerendo rushed 14 times for 85 yards and a touchdown while securing three of four targets for 17 yards in Sunday's 30-24 win over Dallas.

Impact Guerendo took over mid-game after Jordan Mason (shoulder) aggravated a nagging AC joint injury early in the contest. The 24-year-old Guerendo performed as he did the last time this scenario unfolded, which is one of the reasons the rookie was pegged a deep sleeper heading into drafts this year. The downside from a fantasy perspective is that San Francisco will observe its bye this upcoming week, and star running back Christian McCaffrey (Achilles) has a shot at returning in Week 10 against Tampa Bay. Guerendo still is worth looking at if he was dropped prior to Mason's activation Sunday, but be aware of CMC's status come Nov. 10.

OCTOBER 28, 2024 • ROTOWIRE

Takes back seat with starter active Guerendo rushed once for two yards and caught his only target for five yards in Sunday's 28-18 loss to Kansas City.

Impact Guerendo was coming off of his best game as a pro last week (10-99-0), but the rookie took a back seat to Jordan Mason (shoulder) who was able to suit up after suffering a sprained AC joint against the Seahawks in Week 6. The 24-year-old Guerendo saw just two touches when the dust settled from Sunday's loss, fumbling on his lone carry despite not losing possession. With Mason handling his usual workload and Christian McCaffrey (Achilles) nearing a return, it appears that Guerendo can safely be returned to the waiver wire ahead of next Sunday's tilt against the Cowboys.

OCTOBER 21, 2024 • ROTOWIRE

Takes back seat with starter active Guerendo rushed once for two yards and caught his only target for five yards in Sunday's 28-18 loss to Kansas City.

Impact Guerendo was coming off of his best game as a pro last week (10-99-0), but the rookie took a back seat to Jordan Mason (shoulder) who was able to suit up after suffering a sprained AC joint against the Seahawks in Week 6. The 24-year-old Guerendo saw just two touches when the dust settled from Sunday's loss, fumbling on his lone carry despite not losing possession. With Mason handling his usual workload and Christian McCaffrey (Achilles) nearing a return, it appears that Guerendo can safely be returned to the waiver wire ahead of next Sunday's tilt against the Cowboys.

OCTOBER 21, 2024 • ROTOWIRE

Caleb Williams, Jayden Daniels, Drake Maye lead historic week for rookie QBs

This year's class threw the most TD passes ever by rookie QBs in one NFL weekend. Here's a breakdown, along with other Week 6 rookie feats.

OCTOBER 16, 2024

Early Fantasy Football Week 7 Waiver Wire Adds: Isaac Guerendo, Ty Chandler Headline Week 7 Pick Ups Injuries continue to mount across the NFL, so the waiver wire is even more important than ever as we navigate the difficult bye weeks. Heck,...

OCTOBER 14, 2024 • CHARLOTTEOBSERVER.COM

Impressive in expanded role Guerendo rushed 10 times for 99 yards in the 49ers' 36-24 win over the Seahawks on Thursday night.

Impact The rookie saw the most robust volume of his young career in the victory, as Jordan Mason's multiple exits from the game due to a shoulder injury left Guerendo as the lead back for all but one play in the second half. Guerendo had scuffled to just 23 yards on nine carries when he took the handoff on the opening play of the 49ers' final possession, a play on which he broke off a 76-yard run up the right side of the field that he nearly scored on. The rookie fourth-round pick was caught from behind but made sure his momentum didn't carry him into the end zone as he went down, forcing the Seahawks to burn two timeouts before Kyle Juszczyk scored a game-sealing six-yard touchdown. San Francisco has 10 days before a Super Bowl rematch with the Chiefs on Sunday, Oct. 20, but if neither Mason nor Christian McCaffrey (Achilles/calf) is able to suit up for that contest, Guerendo would be in line to serve as San Francisco's No. 1 back for that marquee battle.

OCTOBER 11, 2024 • ROTOWIRE

Season high 22 yards Guerendo rushed five times for 22 yards and was not targeted as a receiver in Sunday's 24-23 loss to Arizona.

Impact Guerendo backed up Jordan Mason (14-89-0) as the rookie had been through the previous four games this season. The 24-year-old Guerendo produced his highest rushing total of his young career while returning a kick for 32 yards in the upset loss. There isn't enough volume currently for the Louisville product to warrant fantasy consideration against the Seahawks on Thursday.

OCTOBER 7, 2024 • ROTOWIRE

Season-high 22 yards Guerendo rushed five times for 22 yards and was not targeted in Sunday's 24-23 loss to Arizona.

Impact Guerendo backed up Jordan Mason (14-89-0) as the rookie had been through the previous four games this season. The 24-year-old Guerendo produced his highest rushing total of his young career while returning a kick for 32 yards in the upset loss. There isn't enough volume currently for the Louisville product to warrant fantasy consideration against the Seahawks on Thursday.

OCTOBER 7, 2024 • ROTOWIRE

Fumbles lone touch on offense Guerendo lost a fumble on his lone carry Sunday, failing to gain any yards while earning zero targets in a blowout win over the Patriots.

Impact Guerendo had a nightmarish game that resulted in a negative fantasy score for anyone bold enough to play the sparsely-used backup against New England. In an effort to not be too harsh on the rookie, it should be noted that he gained 23 yards on San Francisco's only kickoff return attempt Sunday. While Christian McCaffrey (calf/Achilles) mends on IR, it would take another injury to current starter Jordan Mason to give Guerendo fantasy value in standard leagues heading into a Week 5 tilt against Arizona next Sunday.

SEPTEMBER 30, 2024 • ROTOWIRE

Earns five carries Sunday Guerendo rushed five times for 19 yards in Sunday's 27-24 loss to the Rams.

Impact The five carries marked a new high-water mark for the rookie after receiving just one carry for no gain in his first two appearances with San Francisco. Guerendo was spelling fill-in starter Jordan Mason (19-77-0) on Sunday, a situation that could repeat itself against the Patriots on Sunday. The 2024 fourth-round pick only warrants fantasy consideration in the event that Mason is unable to suit up in the coming weeks.

SEPTEMBER 23, 2024 • ROTOWIRE

Earns five carries Sunday Guerendo rushed five times for 19 yards in Sunday's 27-24 loss to the Rams.

Impact The five carries marked a new high-water mark for the rookie after receiving just one carry for no gain in his first two appearances with San Francisco. Guerendo was spelling fill-in starter Jordan Mason (19-77-0) Sunday, a situation which could repeat itself against the Patriots on Sunday. The 2024 fourth-round pick only warrants fantasy consideration in the event that Mason is unable to suit up in the coming weeks.

SEPTEMBER 23, 2024 • ROTOWIRE

No touches on 13 snaps Guerendo (groin) suited up for Monday's season opener against the Jets but did not record a touch in the 32-19 win.

Impact Guerendo made the 49ers' 53-man roster but was battling a groin injury heading into Week 1. The fourth-round pick out of Louisville got the green light and would up logging 10 snaps on special teams and three on offense. Starter Christian McCaffrey (calf/Achilles) did not suit up for this contest, affording fellow backup Jordan Mason (28/147/1) to go off against the Jets. Guerendo appears to be next in line should San Francisco need a runner behind CMC or Mason this season.

SEPTEMBER 10, 2024 • ROTOWIRE

Set to suit up in season opener Guerendo (groin) practiced in full Saturday and doesn't have an injury designation for Monday's Week 1 contest against the Jets.

Impact Guerendo was a limited participant in each of San Francisco's first two practices of the week after missing all of last week due to a groin injury. He is in line to make his NFL debut Monday, though, after returning to a full practice session Saturday. Christian McCaffrey (calf/Achilles) is listed as questionable for the opener against the Jets but has stated that he's definitely suiting up, so Guerendo will likely see limited work in the running game behind the star tailback and backup Jordan Mason.

SEPTEMBER 7, 2024 • ROTOWIRE

Remains limited Guerendo (groin) remained limited in practice Friday, Nick Wagoner of ESPN.com reports.

Impact The rookie missed most of training camp with a hamstring injury and then hurt his groin in late August a week after returning to practice. With Christian McCaffrey (calf) on track to play and Guerendo having taken very few practice reps this summer, there's not much chance of Guerendo having a significant role Week 1 even if he ends up being healthy enough to play.

SEPTEMBER 6, 2024 • ROTOWIRE

Opens week as limited participant Guerendo (groin) is practicing on a limited basis Thursday, Cam Inman of The San Jose Mercury News reports.

Impact Guerendo spent the early portion of training camp sidelined due to a hamstring injury, and he then tweaked his groin after returning for San Francisco's preseason finale. The rookie fourth-round pick will have two more chances to upgrade to full participation in practice ahead of Monday's regular-season opener against the Jets. Meanwhile, top running back Christian McCaffrey (calf/Achilles) will also be limited Thursday, though he's expected to be available Week 1.

SEPTEMBER 5, 2024 • ROTOWIRE

Tweaks groin in practice Guerendo tweaked his groin Monday and won't practice this week, Cam Inman of The San Jose Mercury News reports.

Impact After missing training camp and most of the preseason with a hamstring injury, Guerendo returned for San Francisco's final exhibition and took 13 touches for 35 yards in a 24-24 tie with the Raiders. His depth chart standing seemingly improved despite all the missed time this summer, as long-time No. 2 running back Elijah Mitchell was placed on season-ending injured reserve due to a hamstring injury that will require surgery. Jordan Mason now figures to enter Week 1 as the No. 2 back behind Christian McCaffrey, leaving Guerendo to focus on kickoff returns for the time being. Shanahan said Guerendo could be back at practice as soon as next week, meaning the rookie isn't ruled out for a Week 1 matchup with the Jets on Monday Night Football.

AUGUST 28, 2024 • ROTOWIRE