National Football League

Lions vs. Bills Live Updates, Score: Bills Strike First

Updated: Sep 17, 2026 - 8:43 PM ET

A new era will begin in Buffalo when the Bills host the Detroit Lions on Thursday night. The new Highmark Stadium will play host to its first regular-season game, as the Bills said goodbye to their previous home for 53 seasons at the end of the 2025 season.

Both teams are coming off thrilling Week 1 victories. The Bills scored a game-winning touchdown in the final minutes to take down the Houston Texans, while the Lions were able to outlast the New Orleans Saints in overtime.

Which team will improve to 2-0? Here are all the highlights from Thursday night's game:

7:32p ET

Live Scoreboard:

8:43p ET

Josh Allen Finds Wide-Open Josh Palmer For 43-Yard Touchdown

8:31p ET

Josh Allen Scores First-Ever Touchdown At New Highmark Stadium

7:32p ET

Inactives For Lions-Bills

Live Coverage for this began on 8:33p ET

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National Football League

NFL - Detroit Lions vs. Buffalo Bills - 09/17/2026

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