Rams vs. Panthers 2025 Prediction, Odds, Picks - Nov 30

The Los Angeles Rams (9-2) are heavy favorites (-10) over the Carolina Panthers (6-6). The Rams have won six games in a row. The matchup has an over/under of 45.5 points.

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Rams vs. Panthers Odds & Betting Lines

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Rams vs. Panthers Prediction & Pick

• Pick ATS: Rams (-10)
  
• Pick OU: Under (45.5)
  
• Prediction: Rams 30 - Panthers 12

How to Watch Los Angeles vs. Carolina

• Game date: Sunday, November 30, 2025
• Time: 1 p.m. ET
• Venue: Bank of America Stadium
• Location: Charlotte, North Carolina
• TV: Watch on FOX
• Streaming: FOX One (Limited time offer: 50% off the first two months)

Rams vs. Panthers Recent Matchups

• Los Angeles has a 2-0 record against Carolina in their last two matchups.
• Carolina has been outpaced by 17 points in its last two tilts versus Los Angeles.

Los Angeles Betting Info

• Los Angeles has played 11 games, posting eight wins against the spread.
• The Rams have won their only game this season when playing as at least 10-point favorites.
• Los Angeles games in 2025 have eclipsed the over/under four times in 11 opportunities (36.4%).
• When playing as the moneyline favorite, the Rams have won 90% of the time (9-1).
• Based on this contest's moneyline, the Rams' implied win probability is 85.2%.

Rams Stats

Los Angeles' Key Players

Offense

• Matthew Stafford has 2,830 passing yards (sixth in the NFL), 30 touchdowns (first in the NFL) and two interceptions this year. He has completed 66.5% of his passes, averaging 257.3 yards per game and 7.6 per attempt.
• Kyren Williams' rushing output this season includes 796 yards (10th in the NFL) and six TDs. He's averaging 72.4 yards per game and 4.7 per attempt (14th in the NFL).
• He has caught 24 passes (on 32 targets) for 184 receiving yards with three touchdowns. He's averaging 16.7 receiving yards and 2.2 catches per game.
• Through 11 games played, Davante Adams is averaging 57.4 yards and 4.4 receptions per game on the way to 631 receiving yards and 48 catches. He's been targeted 94 times, and has 12 receiving touchdowns (first in the NFL).
• Puka Nacua has 947 receiving yards (fourth in the NFL) and four touchdowns with 80 catches (third in the NFL) on 98 targets. He's averaging eight receptions and 94.7 yards per game.

Defense

• On the defensive side, Nathan Landman has 97 tackles, five TFL, and 1.5 sacks in 2025. His tackle total leads the Rams and is 10th in the NFL.
• Byron Young has 53 tackles, nine TFL, and nine sacks this season.
• Kamren Curl has recorded 87 tackles, two TFL, one sack, and two interceptions this year. He's second on the Rams in tackles.
• Jared Verse has 40 tackles, nine TFL, six sacks, and one pass defended.

Carolina Betting Info

• Carolina has covered the spread in a game seven times this year (7-5-0).
• This season, the Panthers won ATS in their only game as an underdog of 10 points or more.
• Carolina's games have finished with a final combined score above the over/under six times this season.
• This season, the Panthers have been the underdog 11 times and won six, or 54.5%, of those games.
• The moneyline for this contest implies a 19.0% chance of a victory for the Panthers.

Panthers Stats

Carolina's Key Players

Offense

• Rico Dowdle averages 72.6 rushing yards per game this year (871 total yards to rank seventh in the NFL), while scoring five rushing touchdowns.
• Dowdle has also been a part of the passing attack with 233 yards (19.4 per game) on 27 receptions (2.3 per game), while being targeted 34 times. He has one receiving touchdown.
• Bryce Young has 2,131 passing yards, 15 touchdowns and nine interceptions. His completion percentage is 62.7% and he averages 193.7 yards per game and 6.2 per attempt.
• Bryce Young also has one rushing touchdown and 98 rushing yards (third on the Panthers).
• Through 12 games played this season, Tetairoa McMillan has 56 catches (4.7 receptions per game on eight targets per game) for 783 yards and five receiving touchdowns.
• Chuba Hubbard has scored one touchdown on the ground, while running for 350 total yards (3.7 per carry and 35 per game).
• Hubbard also has 153 receiving yards (15.3 per game) on 21 catches (2.1 per game). He has been targeted 30 times with two touchdown receptions.

Defense

• So far in 2025, Christian Rozeboom has 91 tackles and five TFL over 11 games.
• Trevin Wallace has 52 tackles, four TFL, and two sacks. He is fourth on the Panthers in tackles.
• Mike Jackson Sr. has two TFL, 41 tackles, and two interceptions.
• Derrick Brown has registered three sacks (first on the Panthers) to go with three TFL and 43 tackles over 11 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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