Panthers vs. Saints 2025 Prediction, Odds, Picks - Nov 9

The Carolina Panthers (5-4) are the favorites, expected to win by at least a field goal but less than a touchdown (currently -5.5) over the New Orleans Saints (1-8). The Saints have lost four games straight. The expected point total for the matchup is set at 38.5.

Keep up with the 2025 NFL season on FOX Sports.

Panthers vs. Saints Odds & Betting Lines

This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be compensated. Read more about Sports Betting on FOX Sports.

Panthers vs. Saints Prediction & Pick

• Pick ATS: Panthers (-5.5)
  
• Pick OU: Over (38.5)
  
• Prediction: Panthers 25 - Saints 17

How to Watch Carolina vs. New Orleans

• Game date: Sunday, November 9, 2025
• Time: 1 p.m. ET
• Venue: Bank of America Stadium
• Location: Charlotte, North Carolina
• TV: Watch on FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Panthers vs. Saints Recent Matchups

• Over their last five meetings, New Orleans has three wins against Carolina.
• Over their last five head-to-head contests, New Orleans has put up 124 points, while Carolina has accumulated 66.

Carolina Betting Info

• In nine Carolina games this year, it has six wins against the spread.
• Carolina games in 2025 have eclipsed the over/under five times in nine opportunities (55.6%).
• This is the first time the Panthers are moneyline favorites this season.
• The Panthers have a 71.0% chance to win this matchup, based on the implied probability of the moneyline.

Panthers Stats

Carolina's Key Players

Offense

• Rico Dowdle's rushing output this season includes 735 yards (fourth in the NFL) and four TDs. He's averaging 81.7 yards per game and 5.6 per attempt (third in the NFL).
• Dowdle has 20 targets, 15 catches, 132 receiving yards and one TD through the air.
• Bryce Young has 1,390 passing yards, 11 touchdowns and six interceptions this year. He has completed 61.1% of his attempts, averaging 173.8 yards per game and 5.7 per attempt.
• He has tacked on 78 rushing yards (9.8 per game) and one touchdown on the ground.
• In the passing game, Tetairoa McMillan, has totaled 558 receiving yards and two touchdowns after catching 41 balls on 69 targets. Per game, he's averaging 62 yards and 4.6 receptions over nine games.
• In the running game, Chuba Hubbard averages 3.6 yards per attempt (39th in the NFL) and 42.7 yards per game for 299 total rushing yards. He has scored one rushing touchdown this season.
• Hubbard has been targeted 22 times to the tune of 15 catches, 118 yards and two TDs.

Defense

• On the defensive side for the Panthers, Christian Rozeboom has put up 77 tackles and four TFL in 2025.
• Tre'von Moehrig has 55 tackles, eight TFL, one sack, and one interception this season.
• Trevin Wallace has collected 48 tackles, three TFL, one sack, and four passes defended.
• This season, Derrick Brown has 31 tackles, two TFL, and three sacks.

New Orleans Betting Info

• New Orleans has covered the spread just twice over nine games with a set total.
• This year, the Saints have just one ATS win in four games as an underdog of 5.5 points or more.
• New Orleans games have gone over the total three times this year.
• The Saints have been listed as the underdog eight times this season and have failed to win any of those games.
• The moneyline for this contest implies a 33.3% chance of a victory for the Saints.

Saints Stats

New Orleans' Key Players

Offense

• Through eight games played this year, Spencer Rattler has racked up 1,586 passing yards, with eight touchdowns against five interceptions and completing 67.8% of his attempts.
• On the ground, Rattler has added 167 rushing yards (third on the Saints).
• Chris Olave has 560 receiving yards and three touchdowns on 55 receptions (seventh in the NFL), while being targeted 87 times.
• So far this season through nine games, Alvin Kamara has churned out 377 rushing yards (leading the Saints) and scored one rushing touchdown. He averages 41.9 yards per game and 3.6 per carry (39th in the NFL).
• In addition to his ground game, Kamara has grabbed 28 passes (on 34 targets) for 150 yards (fourth on the Saints). He averages 16.7 yards per game.
• Juwan Johnson has been targeted 56 times, resulting in 39 catches for 399 yards .

Defense

• Demario Davis' 2025 output includes 84 tackles and five TFL through nine games. He leads the Saints and is sixth in the NFL in tackles.
• Pete Werner has 54 tackles, two TFL, and two sacks. He is second on the Saints in tackles.
• Carl Granderson has 33 tackles, six TFL, 4.5 sacks, and two passes defended in the 2025 campaign.
• Jonas Sanker's season stats include 45 tackles, two TFL, and one interception through eight games. He is fourth on the Saints in tackles.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

Want great stories delivered right to your inbox?

Create or log in to your FOX Sports account, follow leagues, teams and players to receive a personalized newsletter daily.