NFL Week 16 Predictions, Betting Odds & TV Schedule

The NFL slate in Week 16, which includes the Baltimore Ravens versus the San Francisco 49ers, is sure to please.

Here is the betting info to analyze prior to Week 16 in the NFL.

Week 16 Betting Lines & Game Info

Los Angeles Rams vs. New Orleans Saints

Odds & Prediction

• Spread: Rams (-4)
• Moneyline: Rams -207, Saints +170
• Total: 45 points
• Prediction: Rams 25, Saints 18

How to Watch

• Game Date: Thursday, December 21
• Game Time: 8:15 PM ET
• TV Channel: Amazon Prime Video
• Location: Inglewood, California

Pittsburgh Steelers vs. Cincinnati Bengals

Odds & Prediction

• Spread: Bengals (-3)
• Moneyline: Bengals -154, Steelers +130
• Total: 38.5 points
• Prediction: Bengals 21, Steelers 19

How to Watch

• Game Date: Saturday, December 23
• Game Time: 4:30 PM ET
• TV Channel: NBC
• Location: Pittsburgh, Pennsylvania

Los Angeles Chargers vs. Buffalo Bills

Odds & Prediction

• Spread: Bills (-12.5)
• Moneyline: Bills -781, Chargers +542
• Total: 44.5 points
• Prediction: Bills 27, Chargers 19

How to Watch

• Game Date: Saturday, December 23
• Game Time: 8:00 PM ET
• TV Channel: Peacock
• Location: Inglewood, California

Minnesota Vikings vs. Detroit Lions

Odds & Prediction

• Spread: Lions (-2.5)
• Moneyline: Lions -142, Vikings +120
• Total: 47.5 points
• Prediction: Lions 24, Vikings 23

How to Watch

• Game Date: Sunday, December 24
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Minneapolis, Minnesota

Tennessee Titans vs. Seattle Seahawks

Odds & Prediction

• Spread: Seahawks (-3)
• Moneyline: Seahawks -164, Titans +138
• Total: 42 points
• Prediction: Seahawks 22, Titans 21

How to Watch

• Game Date: Sunday, December 24
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Nashville, Tennessee

Atlanta Falcons vs. Indianapolis Colts

Odds & Prediction

• Spread: Falcons (-2.5)
• Moneyline: Falcons -149, Colts +125
• Total: 44.5 points
• Prediction: Colts 23, Falcons 20

How to Watch

• Game Date: Sunday, December 24
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Atlanta, Georgia

New York Jets vs. Washington Commanders

Odds & Prediction

• Spread: Jets (-3)
• Moneyline: Jets -157, Commanders +132
• Total: 36.5 points
• Prediction: Jets 24, Commanders 19

How to Watch

• Game Date: Sunday, December 24
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: East Rutherford, New Jersey

Houston Texans vs. Cleveland Browns

Odds & Prediction

• Spread: Browns (-3)
• Moneyline: Browns -159, Texans +135
• Total: 40 points
• Prediction: Browns 23, Texans 20

How to Watch

• Game Date: Sunday, December 24
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Houston, Texas

Carolina Panthers vs. Green Bay Packers

Odds & Prediction

• Spread: Packers (-3.5)
• Moneyline: Packers -194, Panthers +161
• Total: 39.5 points
• Prediction: Packers 24, Panthers 17

How to Watch

• Game Date: Sunday, December 24
• Game Time: 1:00 PM ET
• TV Channel: Watch Online: FOX
• Location: Charlotte, North Carolina

Tampa Bay Buccaneers vs. Jacksonville Jaguars

Odds & Prediction

• Spread: Jaguars (-2)
• Moneyline: Jaguars -126, Buccaneers +105
• Total: 43 points
• Prediction: Buccaneers 23, Jaguars 21

How to Watch

• Game Date: Sunday, December 24
• Game Time: 4:05 PM ET
• TV Channel: CBS
• Location: Tampa, Florida

Chicago Bears vs. Arizona Cardinals

Odds & Prediction

• Spread: Bears (-4.5)
• Moneyline: Bears -210, Cardinals +173
• Total: 42 points
• Prediction: Bears 26, Cardinals 19

How to Watch

• Game Date: Sunday, December 24
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: Chicago, Illinois

Miami Dolphins vs. Dallas Cowboys

Odds & Prediction

• Spread: Dolphins (-1)
• Moneyline: Dolphins -118, Cowboys -102
• Total: 48.5 points
• Prediction: Cowboys 26, Dolphins 25

How to Watch

• Game Date: Sunday, December 24
• Game Time: 4:25 PM ET
• TV Channel: Watch Online: FOX
• Location: Miami Gardens, Florida

Denver Broncos vs. New England Patriots

Odds & Prediction

• Spread: Broncos (-7)
• Moneyline: Broncos -348, Patriots +271
• Total: 37.5 points
• Prediction: Broncos 26, Patriots 14

How to Watch

• Game Date: Sunday, December 24
• Game Time: 8:15 PM ET
• TV Channel: NFL Network
• Location: Denver, Colorado

Kansas City Chiefs vs. Las Vegas Raiders

Odds & Prediction

• Spread: Chiefs (-11)
• Moneyline: Chiefs -621, Raiders +449
• Total: 40.5 points
• Prediction: Chiefs 24, Raiders 15

How to Watch

• Game Date: Monday, December 25
• Game Time: 1:00 PM ET
• TV Channel: CBS
• Location: Kansas City, Missouri

Philadelphia Eagles vs. New York Giants

Odds & Prediction

• Spread: Eagles (-14)
• Moneyline: Eagles -877, Giants +579
• Total: 41.5 points
• Prediction: Eagles 28, Giants 15

How to Watch

• Game Date: Monday, December 25
• Game Time: 4:30 PM ET
• TV Channel: Watch Online: FOX
• Location: Philadelphia, Pennsylvania

San Francisco 49ers vs. Baltimore Ravens

Odds & Prediction

• Spread: 49ers (-6.5)
• Moneyline: 49ers -294, Ravens +237
• Total: 47.5 points
• Prediction: 49ers 26, Ravens 19

How to Watch

• Game Date: Monday, December 25
• Game Time: 8:15 PM ET
• TV Channel: ABC
• Location: Santa Clara, California