2025 NFL Week 18 Predictions, Betting Odds & TV Schedule

In one of the many exciting matchups on the NFL slate in Week 18, the Seattle Seahawks and the San Francisco 49ers take the field at Levi's Stadium.

If you're looking for additional betting information for Week 18 in the NFL, we have you covered with odds for each of the big matchups.

Check out the full NFL schedule on FOX Sports!

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Week 18 Betting Lines & Game Info

Tampa Bay Buccaneers vs. Carolina Panthers

Odds & Prediction

• Spread: Buccaneers (-3)
• Moneyline: Buccaneers -151, Panthers +127
• Total: 43.5 points
• Prediction: Buccaneers 24, Panthers 20

How to Watch

• Game Date: Saturday, Jan. 3
• Game Time: 4:30 p.m. ET
• TV Channel: ABC/ESPN
• Box Score
• Location: Tampa, Florida

San Francisco 49ers vs. Seattle Seahawks

Odds & Prediction

• Spread: Seahawks (-1.5)
• Moneyline: Seahawks -122, 49ers +102
• Total: 47.5 points
• Prediction: Seahawks 25, 49ers 23

How to Watch

• Game Date: Saturday, Jan. 3
• Game Time: 8 p.m. ET
• TV Channel: ABC/ESPN
• Box Score
• Location: Santa Clara, California

Minnesota Vikings vs. Green Bay Packers

Odds & Prediction

• Spread: Vikings (-7.5)
• Moneyline: Vikings -392, Packers +308
• Total: 35.5 points
• Prediction: Vikings 22, Packers 21

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Minneapolis, Minnesota

Jacksonville Jaguars vs. Tennessee Titans

Odds & Prediction

• Spread: Jaguars (-13.5)
• Moneyline: Jaguars -855, Titans +583
• Total: 47.5 points
• Prediction: Jaguars 34, Titans 12

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Jacksonville, Florida

Houston Texans vs. Indianapolis Colts

Odds & Prediction

• Spread: Texans (-10.5)
• Moneyline: Texans -602, Colts +439
• Total: 39 points
• Prediction: Texans 28, Colts 17

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Houston, Texas

Atlanta Falcons vs. New Orleans Saints

Odds & Prediction

• Spread: Falcons (-3.5)
• Moneyline: Falcons -182, Saints +152
• Total: 44 points
• Prediction: Falcons 24, Saints 19

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Atlanta, Georgia

Cincinnati Bengals vs. Cleveland Browns

Odds & Prediction

• Spread: Bengals (-7.5)
• Moneyline: Bengals -385, Browns +300
• Total: 44.5 points
• Prediction: Bengals 28, Browns 19

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 1 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Cincinnati, Ohio

New York Giants vs. Dallas Cowboys

Odds & Prediction

• Spread: Cowboys (-3.5)
• Moneyline: Cowboys -189, Giants +158
• Total: 50 points
• Prediction: Giants 28, Cowboys 25

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 1 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: East Rutherford, New Jersey

Los Angeles Rams vs. Arizona Cardinals

Odds & Prediction

• Spread: Rams (-7.5)
• Moneyline: Rams -329, Cardinals +261
• Total: 46.5 points
• Prediction: Rams 38, Cardinals 12

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Inglewood, California

Buffalo Bills vs. New York Jets

Odds & Prediction

• Spread: Bills (-6.5)
• Moneyline: Bills -316, Jets +255
• Total: 38.5 points
• Prediction: Bills 36, Jets 13

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 4:25 p.m. ET
• TV Channel:
• Box Score
• Location: Orchard Park, New York

Chicago Bears vs. Detroit Lions

Odds & Prediction

• Spread: Bears (-3)
• Moneyline: Bears -157, Lions +132
• Total: 50.5 points
• Prediction: Bears 28, Lions 24

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Chicago, Illinois

New England Patriots vs. Miami Dolphins

Odds & Prediction

• Spread: Patriots (-10.5)
• Moneyline: Patriots -617, Dolphins +457
• Total: 45.5 points
• Prediction: Patriots 31, Dolphins 15

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 4:25 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Foxborough, Massachusetts

Denver Broncos vs. Los Angeles Chargers

Odds & Prediction

• Spread: Broncos (-12.5)
• Moneyline: Broncos -847, Chargers +582
• Total: 37.5 points
• Prediction: Broncos 24, Chargers 19

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 4:25 p.m. ET
• TV Channel:
• Box Score
• Location: Denver, Colorado

Las Vegas Raiders vs. Kansas City Chiefs

Odds & Prediction

• Spread: Chiefs (-5.5)
• Moneyline: Chiefs -276, Raiders +223
• Total: 36.5 points
• Prediction: Chiefs 26, Raiders 15

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 4:25 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Paradise, Nevada

Philadelphia Eagles vs. Washington Commanders

Odds & Prediction

• Spread: Eagles (-4)
• Moneyline: Eagles -200, Commanders +166
• Total: 39 points
• Prediction: Eagles 31, Commanders 13

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 4:25 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Philadelphia, Pennsylvania

Pittsburgh Steelers vs. Baltimore Ravens

Odds & Prediction

• Spread: Ravens (-3.5)
• Moneyline: Ravens -192, Steelers +160
• Total: 40.5 points
• Prediction: Steelers 24, Ravens 23

How to Watch

• Game Date: Sunday, Jan. 4
• Game Time: 8:20 p.m. ET
• TV Channel: NBC/Peacock
• Box Score
• Location: Pittsburgh, Pennsylvania

Learn more about today's games on FOX Sports.

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