Yankees vs. Cardinals Prediction, Odds, Picks - August 17

Alec Burleson and the St. Louis Cardinals hit the field on Sunday at Busch Stadium against Will Warren, who is starting for the New York Yankees. First pitch is at 2:15 p.m. ET. The favored Yankees have -161 moneyline odds to win against the underdog Cardinals, who are listed at +135. New York (-1.5) is the favorite on the run line. The over/under is 9 runs for the contest (with +100 odds to go over and -123 odds to go under).

Take a look at everything you need to know from a betting perspective on the Yankees-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Yankees vs. Cardinals Game Information & Odds

• When: Sunday, August 17, 2025 at 2:15 p.m. ET
• Where: Busch Stadium in St. Louis, Missouri
• How to watch on TV: FDSMW and YES

Yankees vs. Cardinals Prediction

• Score Prediction: Yankees 6, Cardinals 5
• Total Prediction: Over 9 runs
• Win Probabilities: Yankees 51%, Cardinals 49%

Yankees vs. Cardinals Betting Insights

• This season, the Yankees have been favored 103 times and won 57, or 55.3%, of those games.
• This season New York has won 32 of its 51 games, or 62.7%, when favored by at least -161 on the moneyline.
• The implied probability of a win from the Yankees, based on the moneyline, is 61.7%.
• The Cardinals have won in 32, or 48.5%, of the 66 contests they have been named as odds-on underdogs this year.
• St. Louis has a mark of 8-13 in contests where sportsbooks favor it by +135 or worse on the moneyline.
• The moneyline set for this matchup implies the Cardinals have a 42.6% chance of walking away with the win.

Yankees Recent Betting Performance

• The Yankees went 5-3 over the eight games they were moneyline favorites in their last 10 matchups.
• In their last 10 outings (all had set totals), the Yankees combined with their opponents to hit the over on the run total four times.
• The Yankees have a 4-6-0 record against the spread over their past 10 games.

Yankees Recent Stats

Yankees Player Insights

• Aaron Judge's 39 home runs and 91 RBI both lead the Yankees, on top of his team-high .333 average.
• Including all MLB hitters, Judge is first in batting average, first in on-base percentage, and first in slugging.
• Cody Bellinger is batting .267 with 20 doubles, five triples, 22 home runs and 37 walks.
• Bellinger ranks 32nd in home runs and 30th in RBI in the major leagues.
• Anthony Volpe is hitting .215 with 25 doubles, four triples, 18 home runs and 40 walks.
• Trent Grisham has nine doubles, a triple, 21 home runs and 56 walks while batting .250.

Yankees Team Props

Cardinals Recent Betting Performance

• In seven games over the last 10 matchups when set as underdogs by bookmakers, the Cardinals had a record of 3-4.
• The Cardinals and their opponents have combined to hit the over four times in their last 10 games with a total.
• Over their last 10 games, the Cardinals are 4-6-0 against the spread.

Cardinals Recent Stats

Cardinals Player Insights

• Brendan Donovan has 25 doubles, nine home runs and 40 walks while batting .279.
• Among all hitters in the big leagues, Donovan's home run total ranks 179th and his RBI tally is 137th.
• Burleson's .284 batting average leads his team.
• Burleson is 92nd in home runs and 83rd in RBI among all MLB hitters this year.
• Willson Contreras has been solid source of run production for the Cardinals with 16 long balls and 65 runs batted in.
• Masyn Winn has 26 doubles, nine home runs and 31 walks while batting .267.

Cardinals Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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