Twins vs. Orioles Prediction, Odds, Picks - May 14

Updated May. 13, 2025 4:01 p.m. ET

Data Skrive

The Minnesota Twins and Baltimore Orioles will meet on Wednesday at Oriole Park at Camden Yards, at 3:35 p.m. ET, with Byron Buxton and Cedric Mullins among those expected to step up at the plate. The Twins are listed as -111 moneyline favorites for this matchup against the Orioles (-107). Minnesota is the favorite on the run line (-1.5 with +150 odds). The over/under is 8.5 runs for this contest.

Take a look at everything you need to know from a betting perspective on the Twins-Orioles game, regarding the run line, moneyline and total, plus expert picks.

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Trevor Larnach crushes two-run home run, giving Twins lead over Giants

Trevor Larnach crushed a two-run home run to give the Minnesota Twins the lead over the San Francisco Giants.

Twins vs. Orioles Game Information & Odds

When: Wednesday, May 14, 2025 at 3:35 p.m. ET
Where: Oriole Park at Camden Yards in Baltimore, Maryland
How to watch on TV: MASN2 and MNNT

Favorite	Favorite Moneyline	Underdog Moneyline	Total	Over Total Odds	Under Total Odds	Run Line	Favorite Run Line Odds	Underdog Run Line Odds
Twins	-111	-107	8.5	-125	+105	-1.5	+150	-182

Twins vs. Orioles Prediction

Score Prediction: Twins 6, Orioles 5
Total Prediction: Over 8.5 runs
Win Probabilities: Twins 53%, Orioles 47%

Twins vs. Orioles Betting Insights

The Twins have won 15, or 55.6%, of the 27 games they've played as favorites this season.
Minnesota has a record of 15-12 in games when sportsbooks favor them by at least -111 on the moneyline.
The sportsbooks' moneyline implies a 52.6% chance of a victory for the Twins.
The Orioles have been victorious in six, or 35.3%, of the 17 contests they have been chosen as underdogs in this season.
This year, Baltimore has won six of 17 games when listed as at least -107 or worse on the moneyline.
The Orioles have an implied victory probability of 51.7% according to the moneyline set for this matchup.

Twins Recent Betting Performance

The Twins were the moneyline favorite for five of their last 10 games, and they finished 4-1 in those matchups.
Over their last 10 outings (all had set totals), the Twins combined with their opponents to hit the over on the run total three times.
The Twins have put together a 7-3-0 record against the spread over their past 10 games.

Twins Recent Stats

Stat	Avg/Total
Record	8-2
Runs Per Game	4.4
HR	10
ERA	2.70
K/9	9.8

Twins Player Insights

Buxton leads the Twins with nine home runs and 26 runs batted in, while putting up a team-high batting average of .264.
Among all MLB batters, Buxton ranks 61st in batting average, 110th in on-base percentage, and 18th in slugging.
Trevor Larnach is batting .245 with four doubles, six home runs and 16 walks.
Larnach is 61st in home runs and 72nd in RBI in the bigs.
Larnach heads into this game looking for his fifth game in a row with a hit. In his last five games he is hitting .333 with two doubles, two home runs and four RBIs.
Ty France has eight doubles, three home runs and 10 walks while batting .260.
Harrison Bader is batting .298 with five doubles, four home runs and 12 walks.
Bader has recorded at least one hit in three straight games. In his last five games he is hitting .455 with a double, a home run, three walks and three RBIs.

Orioles Recent Betting Performance

The Orioles have played as underdogs in three of their past 10 games and lost each of those contests.
When it comes to hitting the over, the Orioles and their opponents are 3-7-0 in their last 10 games with a total.
The Orioles have a record of 4-6-0 ATS over their last 10 games.

Orioles Recent Stats

Stat	Avg/Total
Record	4-6
Runs Per Game	3.2
HR	11
ERA	4.71
K/9	7.7

Orioles Player Insights

Mullins paces the Orioles in home runs (seven) and runs batted in (21).
Among all batters in MLB, Mullins' home run total is 41st and his RBI tally ranks 57th.
Ryan O'Hearn's seven home runs pace his team.
Among all MLB hitters, O'Hearn ranks 41st in homers and 150th in RBI.
Adley Rutschman is hitting .203 with four doubles, a triple, four home runs and 18 walks.
Gunnar Henderson leads the Orioles with a .264 batting average.