Twins vs. Angels Prediction, Odds, Picks - April 25

Byron Keiron Buxton and the Minnesota Twins will see Kyle Hendricks at the rubber for the Los Angeles Angels in the first game of a three-game series, Friday at 7:40 p.m. ET. The Twins have been listed as -204 moneyline favorites for this matchup with the Angels (+170). Minnesota is the favorite on the run line (-1.5). The matchup's total is set at 8 runs.

Here's everything you need from a betting perspective on the Twins-Angels game, regarding the run line, moneyline and total, plus expert picks.

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Twins vs. Angels Game Information & Odds

• When: Friday, April 25, 2025 at 7:40 p.m. ET
• Where: Target Field in Minneapolis, Minnesota
• How to watch on TV: MNNT and FDSW

Twins vs. Angels Prediction

• Score Prediction: Twins 4, Angels 3
• Total Prediction: Under 8 runs
• Win Probabilities: Twins 52%, Angels 48%

Twins vs. Angels Betting Insights

• This season, the Twins have won eight out of the 18 games, or 44.4%, in which they've been favored.
• Minnesota is 2-1 this season when entering a game favored by -204 or more on the moneyline.
• The Twins have a 67.1% chance to win this game based on the implied probability of the moneyline.
• The Angels have come away with eight wins in the 16 contests they have been listed as the underdogs in this season.
• Los Angeles has yet to play a game this season with longer moneyline odds than +170.
• The moneyline set for this matchup implies the Angels have a 37% chance of walking away with the win.

Twins Recent Betting Performance

• The Twins went 4-2 over the six games they were favored on the moneyline in their last 10 matchups.
• In their last 10 matchups (all had set totals), the Twins combined with their opponents to go over the total three times.
• The Twins have a 5-5-0 record against the spread over their past 10 games.

Twins Recent Stats

Twins Player Insights

• The Twins' best power option comes in the form of Buxton and his five-dinger 12-RBI season, both team highs.
• Buxton's home runs put him 32nd in the majors, and he is 72nd in RBI.
• Ty France has a club-leading 12 runs batted in and .233 batting average.
• France is 131st in homers and 72nd in RBI among all hitters in baseball.
• Trevor Larnach is batting .210 with a double, three home runs and 12 walks.
• Carlos Javier Correa is batting .167 with six doubles, a home run and six walks.

Twins Team Props

Angels Recent Betting Performance

• The Angels have played as underdogs in five of their past 10 games and won one of those contests.
• In their last 10 games with a total, the Angels and their opponents have combined to hit the over two times.
• The Angels have a record of 3-7-0 ATS over their last 10 games.

Angels Recent Stats

Angels Player Insights

• Mike Trout has put up a team-high eight home runs and has driven in 16 runs.
• Among all hitters in the big leagues, Trout ranks fourth in homers and 25th in RBI.
• Taylor Ward is hitting .214 with four doubles, six home runs and five walks.
• Ward is 18th overall in homers and 114th in RBI this season.
• Nolan Schanuel leads the Angels with a team-best batting average of .256.
• Kyren Paris is hitting .246 with a double, a triple, five home runs and five walks.

Angels Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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