Royals vs. Cardinals Prediction, Odds, Picks - May 16

Maikel Garcia and the Kansas City Royals will meet Brendan Donovan and the St. Louis Cardinals on Friday at Kauffman Stadium, at 7:40 p.m. ET. The Cardinals are +131 moneyline underdogs for this matchup with the Royals (-156). Kansas City is favored on the run line (-1.5). The matchup's over/under has been set at 8.5 runs.

Here is everything you need from a betting perspective on the Royals-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Royals vs. Cardinals Game Information & Odds

• When: Friday, May 16, 2025 at 7:40 p.m. ET
• Where: Kauffman Stadium in Kansas City, Missouri
• How to watch on TV: FDSKC and FDSMW

Royals vs. Cardinals Prediction

• Score Prediction: Royals 5, Cardinals 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Royals 51%, Cardinals 49%

Royals vs. Cardinals Betting Insights

• The Royals have won 13, or 68.4%, of the 19 games they've played as favorites this season.
• This season Kansas City has won seven of its eight games when favored by at least -156 on the moneyline.
• The implied probability of a win from the Royals, based on the moneyline, is 60.9%.
• The Cardinals have come away with 16 wins in the 30 contests they have been listed as the underdogs in this season.
• St. Louis has a win-loss record of 3-6 when favored by +131 or worse by bookmakers this year.
• The Cardinals have an implied victory probability of 43.3% according to the moneyline set for this matchup.

Royals Recent Betting Performance

• The Royals have a 4-2 record over the six games they were a moneyline favorite in their last 10 matchups.
• Over their last 10 matchups (all 10 of them had set totals), the Royals and their opponents combined to go over the run total three times.
• The Royals have put together a 6-4-0 record against the spread over their past 10 games.

Royals Recent Stats

Royals Player Insights

• Bobby Witt Jr. is the Royals best hitter, putting together an average of .312 while also being the team's top run producer, delivering 25 RBI and launching five long balls.
• Witt is 96th in homers and 37th in RBI among all hitters in MLB.
• Garcia is hitting .295 with 11 doubles, a triple, five home runs and 17 walks.
• Garcia is 96th in home runs and 97th in RBI in the majors.
• Vinnie Pasquantino paces the Royals in home runs (six) and runs batted in (25).
• Jonathan India is batting .244 with nine doubles, a home run and 21 walks.
• India has recorded at least one hit in three straight games. During his last five outings he is batting .286 with a double, a walk and three RBIs.

Royals Team Props

Cardinals Recent Betting Performance

• In six games as underdogs over the last 10 matchups, the Cardinals have a record of 5-1.
• The Cardinals and their opponents have combined to hit the over four times in their last 10 games with a total.
• In their last 10 games with a spread, the Cardinals covered each time.

Cardinals Recent Stats

Cardinals Player Insights

• Lars Nootbaar has collected a team-best seven home runs.
• Nootbaar's home run total places him 48th in the majors, and he is 48th in RBI.
• Nootbaar brings a hitting streak of seven games into this game. In his last 10 outings he is hitting .293 with three doubles, two home runs, six walks and six RBIs.
• Donovan's .313 batting average is a team-high mark.
• Donovan ranks 166th in homers and 83rd in RBI among all MLB hitters this season.
• Nolan Arenado is hitting .253 with 10 doubles, four home runs and 17 walks.
• Willson Contreras has plated a team-best 25 runs batted in.

Cardinals Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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