Phillies vs. Twins Prediction, Odds, Picks - September 28

Edmundo Sosa and the Philadelphia Phillies will take on the Minnesota Twins and Trevor Larnach on Sunday at 3:05 p.m. ET, at Citizens Bank Park. The Twins are listed as +203 moneyline underdogs for this matchup against the favored Phillies (-251). Philadelphia is the favorite on the run line (-1.5). The total is 8 runs for this matchup.

Check out everything you need to know from a betting perspective on the Phillies-Twins game, regarding the run line, moneyline and total, plus expert picks.

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Phillies vs. Twins Game Information & Odds

• When: Sunday, September 28, 2025 at 3:05 p.m. ET
• Where: Citizens Bank Park in Philadelphia, Pennsylvania
• How to watch on TV: NBCS-PH and MNNT

Phillies vs. Twins Prediction

• Score Prediction: Phillies 5, Twins 3
• Total Prediction: Under 8 runs
• Win Probabilities: Phillies 59%, Twins 41%

Phillies vs. Twins Betting Insights

• The Phillies have won 79, or 61.7%, of the 128 games they've played as favorites this season.
• Philadelphia has entered 10 games this season favored by -251 or more and is 9-1 in those contests.
• The Phillies have a 71.5% chance to win this game based on the implied probability of the moneyline.
• The Twins have been underdogs in 70 games this season and have come away with the win 28 times (40%) in those contests.
• Minnesota has played as an underdog of +203 or more just one time this year and came away with a loss in that game.
• The moneyline set for this matchup implies the Twins have a 33% chance of walking away with the win.

Phillies Recent Betting Performance

• The Phillies were the moneyline favorite for six of their last 10 games, and they finished 3-3 in those matchups.
• Over their last 10 matchups, the Phillies and their opponents combined to go over the run total five times (all 10 of the games had set totals).
• The Phillies' ATS record is 4-6-0 over their past 10 games.

Phillies Recent Stats

Phillies Player Insights

• Kyle Schwarber leads the Phillies in home runs (56) and runs batted in (132).
• In all of the majors, Schwarber ranks second in homers and first in RBI.
• Bryce Harper is hitting .264 with 32 doubles, 27 home runs and 70 walks.
• Harper ranks 37th in homers and 67th in RBI in the majors.
• Harper has four straight games with at least one hit. During his last five outings he is hitting .211 with two walks.
• Bryson Stott has 22 doubles, three triples, 13 home runs and 54 walks while hitting .256.
• Nick Castellanos is hitting .252 with 27 doubles, two triples, 17 home runs and 32 walks.

Phillies Team Props

Twins Recent Betting Performance

• In nine games as underdogs over the last 10 matchups, the Twins have a record of 4-5.
• The Twins and their opponents have combined to hit the over just once in their last 10 games with a total.
• The Twins have won four of their last 10 games against the spread.

Twins Recent Stats

Twins Player Insights

• Byron Buxton leads the Twins in home runs (35), runs batted in (83) and has a team-best batting average of .264.
• Among all hitters in MLB, Buxton is 12th in homers and 45th in RBI.
• Larnach is batting .249 with 23 doubles, a triple, 17 home runs and 53 walks.
• Larnach is currently 111th in home runs and 130th in RBI in the big leagues.
• Brooks Lee is batting .236 with 15 doubles, a triple, 16 home runs and 30 walks.
• Ryan Jeffers has 25 doubles, nine home runs and 49 walks while batting .261.

Twins Team Props

Twins vs. Rangers Highlights | MLB on FOX

Check out the best moments between the Minnesota Twins and Texas Rangers.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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