Cubs vs. Royals Prediction, Odds, Picks - July 23

Seth Lugo will start for the Kansas City Royals aiming to take down Carson Kelly and the Chicago Cubs on Wednesday at 2:20 p.m. ET. The Cubs are listed as -260 moneyline favorites in this matchup with the Royals (+210). Chicago is the favorite on the run line (-1.5). A 9-run total is set in the contest.

Here's everything you need from a betting perspective on the Cubs-Royals game, regarding the run line, moneyline and total, plus expert picks.

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Royals vs. Cubs Highlights | MLB on FOX

Check out the best moments between the Kansas City Royals and Chicago Cubs.

Cubs vs. Royals Game Information & Odds

• When: Wednesday, July 23, 2025 at 2:20 p.m. ET
• Where: Wrigley Field in Chicago, Illinois
• How to watch on TV: MARQ and FDSKC

Cubs vs. Royals Prediction

• Score Prediction: Cubs 5, Royals 4
• Total Prediction: Under 9 runs
• Win Probabilities: Cubs 57%, Royals 43%

Cubs vs. Royals Betting Insights

• This season, the Cubs have won 48 out of the 69 games, or 69.6%, in which they've been favored.
• Chicago has been at least -260 moneyline favorites eight times this season and won each of those games.
• The sportsbooks' moneyline implies a 72.2% chance of a victory for the Cubs.
• The Royals have been chosen as underdogs in 63 games this year and have walked away with the win 29 times (46%) in those games.
• This will be the worst odds to win that sportsbooks have given Kansas City this season with a +210 moneyline set for this game.
• Sportsbooks have implied with the moneyline set for this matchup that the Royals have a 32.3% chance of pulling out a win.

Cubs Recent Betting Performance

• The Cubs played as the moneyline favorite for five of their last 10 games, and went 4-1 in those matchups.
• Over their last 10 outings (all had set totals), the Cubs combined with their opponents to go over the total three times.
• The Cubs are 6-4-0 against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Kyle Tucker is batting .275 with 19 doubles, four triples, 18 home runs and 65 walks.
• Including all MLB hitters, Tucker ranks 45th in batting average, seventh in on-base percentage, and 24th in slugging.
• Pete Crow-Armstrong has put his power on display as he leads his team with 26 home runs.
• Crow-Armstrong ranks sixth in home runs in the majors, and ninth in RBI.
• Crow-Armstrong heads into this game looking for his sixth game in a row with a hit. In his last five games he is hitting .333 with four doubles, a home run and three RBIs.
• Seiya Suzuki leads the Cubs in home runs (26) and runs batted in (81).
• Nico Hoerner has a club-high .286 batting average.

Cubs Team Props

Royals Recent Betting Performance

• The Royals have played as underdogs in four of their past 10 games and have gone 1-3 in those contests.
• The Royals and their opponents have combined to hit the over four times in their last 10 games with a total.
• The Royals are 3-7-0 ATS over their last 10 games.

Royals Recent Stats

Royals Player Insights

• Bobby Witt Jr. is batting .288 with 33 doubles, three triples, 14 home runs and 31 walks, while getting on base at a rate of .339.
• Witt ranks 65th in homers and 41st in RBI among all hitters in MLB.
• Witt carries a three-game hitting streak into this matchup. During his last five outings he is batting .182 with a double, a walk and two RBIs.
• Maikel Garcia has a club-best .291 batting average.
• Garcia is 157th in homers and 99th in RBI among all batters in MLB.
• Vinnie Pasquantino is batting .264 with 14 doubles, a triple, 15 home runs and 29 walks.
• Salvador Perez leads the Royals in home runs (17) and runs batted in (60).

Royals Team Props

Royals vs. Cubs Highlights | MLB on FOX

Check out the best moments between the Kansas City Royals and Chicago Cubs.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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