Penn State vs. UCLA Prediction, Odds, Picks - October 4, 2025

Updated Oct. 4, 2025 3:05 p.m. ET

FOX Sports

The No. 7 Penn State Nittany Lions (3-1) are 24.5-point favorites when they visit the UCLA Bruins (0-4) in a Big Ten matchup on Saturday, October 4, 2025 at the Rose Bowl. The point total is set at 48.5 for the game.

In their most recent action, the Nittany Lions lost versus the Oregon Ducks, 30-24. The Bruins lost to the Northwestern Wildcats, 17-14, in their last game.

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Penn State vs. UCLA Game Information & Odds

When: Saturday, October 4, 2025 at 3:30 p.m. ET
Location: Rose Bowl in Pasadena, California
TV: CBS
Live Box Score on FOX Sports

Penn State vs UCLA Betting Information updated as of October 4, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Penn State	-24.5 (-109)	-2632	+1250	48.5	-112	-108

Penn State vs. UCLA Prediction

Pick ATS: UCLA (+24.5)
Pick OU: Under (48.5)
Prediction: Penn State 33, UCLA 14

Predictions are made by the Data Skrive betting model.

Learn more about the Penn State Nittany Lions vs. the UCLA Bruins game on FOX Sports!

Penn State vs. UCLA Betting Insights

Per the spread and over/under, the implied score for the game is Nittany Lions 36, Bruins 12.
The Nittany Lions have a 96.3% chance to collect the win in this game based on the moneyline's implied probability. The Bruins have a 7.4% implied probability.
Penn State is winless against the spread this season (0-4-0).
UCLA has won one game against the spread this year.

Penn State vs. UCLA: 2025 Stats Comparison

	Penn State	UCLA
Off. Points per Game (Rank)	39 (36)	14.3 (134)
Def. Points per Game (Rank)	11.8 (7)	31.3 (91)
Turnovers Allowed (Rank)	2 (8)	4 (25)
Turnovers Forced (Rank)	7 (38)	2 (126)

Penn State 2025 Key Players

Name	Position	Stats
Kaytron Allen	RB	327 YDS / 4 TD / 81.8 YPG / 7.1 YPC
Drew Allar	QB	763 YDS (62.8%) / 6 TD / 2 INT 69 RUSH YDS / 0 RUSH TD / 17.3 RUSH YPG
Nicholas Singleton	RB	200 YDS / 5 TD / 50 YPG / 3.8 YPC 8 REC / 73 REC YDS / 0 REC TD / 18.3 REC YPG
Trebor Pena	WR	15 REC / 182 YDS / 1 TD / 45.5 YPG
Amare Campbell	LB	36 TKL / 3 TFL / 1 SACK
Dani Dennis-Sutton	DL	16 TKL / 3 TFL / 2 SACK
Tony Rojas	LB	24 TKL / 4 TFL / 2 SACK
Zakee Wheatley	DB	18 TKL / 0 TFL

UCLA 2025 Key Players

Name	Position	Stats
Nico Iamaleava	QB	788 YDS (65.3%) / 4 TD / 3 INT 204 RUSH YDS / 1 RUSH TD / 51 RUSH YPG
Anthony Woods	RB	127 YDS / 0 TD / 31.8 YPG / 5.1 YPC 13 REC / 103 REC YDS / 1 REC TD / 25.8 REC YPG
Kwazi Gilmer	WR	19 REC / 225 YDS / 1 TD / 56.3 YPG
Jaivian Thomas	RB	117 YDS / 0 TD / 29.3 YPG / 5.1 YPC 5 REC / 42 REC YDS / 0 REC TD / 14 REC YPG
JonJon Vaughns	LB	38 TKL / 1 TFL
Isaiah Chisom	LB	33 TKL / 1 TFL
Cole Martin	DB	22 TKL / 1 TFL
Gary Smith III	DL	17 TKL / 1 TFL / 0.5 SACK