Marshall vs. Louisiana Prediction, Odds, Picks - September 27, 2025

The Louisiana Ragin' Cajuns (1-3) are slight, 2.5-point underdogs in a home Sun Belt matchup against the Marshall Thundering Herd (2-2) on Saturday, September 27, 2025 at Cajun Field at Our Lady of Lourdes Stadium. The point total is 48.5 for the outing.

The Thundering Herd beat the Middle Tennessee Blue Raiders, 42-28, in their last contest. The Ragin' Cajuns' last contest was against the Eastern Michigan Eagles, and they lost by a score of 34-31.

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Marshall vs. Louisiana Game Information & Odds

• When: Saturday, September 27, 2025 at 8 p.m. ET
• Location: Cajun Field at Our Lady of Lourdes Stadium in Lafayette, Louisiana
• TV: ESPN+
• Live Box Score on FOX Sports

Marshall vs. Louisiana Prediction

• Pick ATS: Louisiana (+2.5)
  
• Pick OU: Over (48.5)
  
• Prediction: Louisiana 27, Marshall 26

Predictions are made by the Data Skrive betting model.

Learn more about the Marshall Thundering Herd vs. the Louisiana Ragin' Cajuns game on FOX Sports!

Marshall vs. Louisiana Betting Insights

• Based on the spread and over/under, the implied score for the matchup is Thundering Herd 26, Ragin' Cajuns 23.
• The Thundering Herd have a 55.6% chance to win this game per the moneyline's implied probability. The Ragin' Cajuns hold a 48.8% implied probability.
• Marshall has put together a 3-1-0 ATS record so far this year.
• Louisiana is winless against the spread this year (0-3-0).

Marshall vs. Louisiana: Head-to-Head

• Louisiana has a 2-1 record against Marshall in their last three matchups.
• The last three times the Ragin' Cajuns have played the Thundering Herd, they have a 2-1 record against the spread. The scoring has gone over the point total on one occasion.
• Over their last three head-to-head contests, Marshall has put up 65 points, while Louisiana has posted 62.

Marshall vs. Louisiana: 2025 Stats Comparison

Marshall 2025 Key Players

Louisiana 2025 Key Players

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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