Kansas State vs. Iowa State Prediction, Odds, Picks - August 23, 2025

Updated Aug. 23, 2025 9:04 a.m. ET

Data Skrive

Aviva Stadium in Dublin, Ireland is the setting for the No. 17 Kansas State Wildcats' (0-0) matchup against the No. 22 Iowa State Cyclones (0-0) on August 23, 2025, starting at 12 p.m. ET, airing on ESPN. The Wildcats are a 3.5-point favorite in the game. The total has been set at 50.5 points for this game.

The Wildcats finished 9-4 last season and won the Rate Bowl. They scored 30.8 points per game (46th in college football) and allowed 23.4 (49th).

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Kansas State vs. Iowa State Game Information & Odds

When: Saturday, August 23, 2025 at 12 p.m. ET
Location: Aviva Stadium in Dublin, Ireland
TV: ESPN
Live Box Score on FOX Sports

Kansas State vs Iowa State Betting Information updated as of August 23, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Kansas State	-3.5 (-105)	-163	+138	50.5	-115	-105

Kansas State vs. Iowa State Prediction

Pick ATS: Iowa State (+3.5)
Pick OU: Over (50.5)
Prediction: Kansas State 28, Iowa State 27

Predictions are made by the Data Skrive betting model.

Learn more about the Kansas State Wildcats vs. the Iowa State Cyclones game on FOX Sports!

Kansas State vs. Iowa State Betting Insights

Based on the spread and over/under, the implied score for the game is Wildcats 27, Cyclones 24.
The Wildcats have a 62.0% chance to claim victory in this meeting per the moneyline's implied probability. The Cyclones hold a 42.0% implied probability.
Kansas State covered four times in 13 matchups with a spread last season.
Iowa State compiled an 8-5-0 record against the spread last year.

Kansas State vs. Iowa State: Head-to-Head

In their last four head-to-head bouts, Iowa State has beaten Kansas State three times.
The Cyclones carry a 3-0-1 record ATS in those games, while the two teams have gone over the total on two occasions.
Kansas State has been outscored by 27 points in its last four tilts versus Iowa State.

Kansas State vs. Iowa State: 2024 Stats Comparison

	Kansas State	Iowa State
Off. Points per Game (Rank)	30.8 (46)	31.1 (28)
Def. Points per Game (Rank)	23.4 (48)	22.9 (68)
Turnovers Allowed (Rank)	16 (47)	15 (33)
Turnovers Forced (Rank)	15 (88)	24 (17)

Kansas State 2024 Key Players

Name	Position	Stats
Avery Johnson	QB	2,712 YDS (58.3%) / 25 TD / 10 INT 605 RUSH YDS / 7 RUSH TD / 46.5 RUSH YPG
DJ Giddens	RB	1,343 YDS / 7 TD / 111.9 YPG / 6.6 YPC 21 REC / 258 REC YDS / 1 REC TD / 21.5 REC YPG
Dylan Edwards	RB	546 YDS / 5 TD / 45.5 YPG / 7.4 YPC 19 REC / 133 REC YDS / 2 REC TD / 12.1 REC YPG
Jayce Brown	WR	47 REC / 823 YDS / 5 TD / 63.3 YPG
Austin Romaine	LB	79 TKL / 5 TFL / 2 SACK
Brendan Mott	DL	38 TKL / 7 TFL / 8.5 SACK / 1 INT
Desmond Purnell	LB	37 TKL / 7 TFL / 4 SACK
Marques Sigle	DB	47 TKL / 4 TFL / 3 INT / 3 PD

Iowa State 2024 Key Players

Name	Position	Stats
Rocco Becht	QB	3,505 YDS (59.5%) / 25 TD / 9 INT 318 RUSH YDS / 8 RUSH TD / 22.7 RUSH YPG
Carson Hansen	RB	752 YDS / 13 TD / 53.7 YPG / 5 YPC 13 REC / 88 REC YDS / 2 REC TD / 8 REC YPG
Jayden Higgins	WR	87 REC / 1,183 YDS / 9 TD / 91 YPG
Jaylin Noel	WR	81 REC / 1,194 YDS / 8 TD / 85.3 YPG
Beau Freyler	DB	67 TKL / 2 TFL / 2 INT / 2 PD
Malik Verdon	DB	58 TKL / 4 TFL / 1 SACK / 1 INT
Kooper Ebel	LB	58 TKL / 3 TFL / 1 SACK
Jontez Williams	DB	39 TKL / 2 TFL / 4 INT / 4 PD