Kansas State vs. Colorado Prediction, Odds, Picks - November 29, 2025

Updated Nov. 29, 2025 9:04 a.m. ET

FOX Sports

The Kansas State Wildcats (5-6) are 17.5-point favorites when they host the Colorado Buffaloes (3-8) in a Big 12 matchup on Saturday, November 29, 2025 at Bill Snyder Family Stadium. The total is 50.5 points for this game.

The Wildcats' last game was against the Utah Utes, and they lost by a score of 51-47. The Buffaloes' last game was against the Arizona State Sun Devils, and they lost by a score of 42-17.

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Kansas State vs. Colorado Game Information & Odds

When: Saturday, November 29, 2025 at 12 p.m. ET
Location: Bill Snyder Family Stadium in Manhattan, Kansas
TV: FS1
Streaming: FOX One (Limited time offer: 50% off the first two months)

Kansas State vs Colorado Betting Information updated as of November 29, 2025, 8:45 a.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Kansas State	-17.5 (-106)	-901	+597	50.5	-109	-111

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Kansas State vs. Colorado Prediction

Pick ATS: Colorado (+17.5)
Pick OU: Over (50.5)
Prediction: Kansas State 34, Colorado 20

Predictions are made by the Data Skrive betting model.

Learn more about the Kansas State Wildcats vs. the Colorado Buffaloes game on FOX Sports!

Kansas State vs. Colorado Betting Insights

Based on the spread and over/under, the implied score for the matchup is Wildcats 34, Buffaloes 16.
The Wildcats have a 90.0% chance to claim victory in this meeting per the moneyline's implied probability. The Buffaloes hold a 14.3% implied probability.
Kansas State is 5-6-0 ATS this season.
Colorado is 4-7-0 ATS this year.

Kansas State vs. Colorado: 2025 Stats Comparison

	Kansas State	Colorado
Off. Points per Game (Rank)	29.9 (56)	21.5 (113)
Def. Points per Game (Rank)	27.8 (88)	31.1 (110)
Turnovers Allowed (Rank)	15 (77)	16 (87)
Turnovers Forced (Rank)	25 (3)	15 (54)

Kansas State 2025 Key Players

Name	Position	Stats
Avery Johnson	QB	2,265 YDS (59.9%) / 18 TD / 6 INT 441 RUSH YDS / 8 RUSH TD / 40.1 RUSH YPG
Joe Jackson	RB	769 YDS / 5 TD / 76.9 YPG / 5.4 YPC 21 REC / 120 REC YDS / 1 REC TD / 12 REC YPG
Jayce Brown	WR	41 REC / 712 YDS / 5 TD / 79.1 YPG
Garrett Oakley	TE	38 REC / 389 YDS / 6 TD / 35.4 YPG
Desmond Purnell	LB	56 TKL / 3 TFL / 2.5 SACK / 2 INT
Zashon Rich	DB	51 TKL / 2 TFL / 1 SACK / 1 INT
Austin Romaine	LB	55 TKL / 4 TFL / 0.5 SACK / 1 INT
VJ Payne	DB	52 TKL / 0 TFL / 1 INT / 1 PD

Colorado 2025 Key Players

Name	Position	Stats
Kaidon Salter	QB	1,242 YDS (63.1%) / 10 TD / 6 INT 294 RUSH YDS / 5 RUSH TD / 36.8 RUSH YPG
Omarion Miller	WR	37 REC / 687 YDS / 8 TD / 68.7 YPG
Joseph Williams	WR	37 REC / 489 YDS / 4 TD / 48.9 YPG
Micah Welch	RB	364 YDS / 2 TD / 33.1 YPG / 4.2 YPC
Tawfiq Byard	DB	60 TKL / 3 TFL / 0.5 SACK / 1 INT
Jeremiah Brown	LB	56 TKL / 6 TFL / 2 SACK
Keaten Wade	DL	40 TKL / 6 TFL / 2.5 SACK
Preston Hodge	DB	38 TKL / 1 TFL / 1 INT / 1 PD