Kansas State vs. Arizona Prediction, Odds, Picks - September 12, 2025

Updated Sep. 12, 2025 3:04 p.m. ET

FOX Sports

Oddsmakers project a competitive game when the Kansas State Wildcats (1-2) visit the Arizona Wildcats (2-0) on Friday, September 12, 2025 in a matchup between Big 12 rivals at Arizona Stadium. Kansas State is favored by 1.5 points. The contest has a 54.5-point over/under.

The Kansas State Wildcats' most recent contest was against the Army Black Knights, and they lost by a score of 24-21. The Arizona Wildcats beat the Weber State Wildcats, 48-3, in their most recent contest.

Keep up with college football all season on FOX Sports.

Kansas State vs. Arizona Game Information & Odds

When: Friday, September 12, 2025 at 9 p.m. ET
Location: Arizona Stadium in Tucson, Arizona
TV: FOX
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Kansas State vs Arizona Betting Information updated as of September 12, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Kansas State	-1.5 (-108)	-118	-102	54.5	-110	-110

Kansas State vs. Arizona Prediction

Pick ATS: Arizona (+1.5)
Pick OU: Under (54.5)
Prediction: Arizona 25, Kansas State 21

Predictions are made by the Data Skrive betting model.

Learn more about the Kansas State Wildcats vs. the Arizona Wildcats game on FOX Sports!

Kansas State vs. Arizona Betting Insights

Per the spread and over/under, the implied score for the matchup is Kansas State Wildcats 28, Arizona Wildcats 26.
The Kansas State Wildcats have a 54.1% chance to collect the win in this contest per the moneyline's implied probability. The Arizona Wildcats have a 50.5% implied probability.
Kansas State is winless against the spread this season (0-3-0).
Arizona has put together a perfect 1-0-0 record against the spread this season.

Kansas State vs. Arizona: 2025 Stats Comparison

	Kansas State	Arizona
Off. Points per Game (Rank)	26.7 (37)	44 (26)
Def. Points per Game (Rank)	27.7 (130)	4.5 (4)
Turnovers Allowed (Rank)	4 (109)	0 (1)
Turnovers Forced (Rank)	3 (35)	7 (1)

Kansas State 2025 Key Players

Name	Position	Stats
Avery Johnson	QB	763 YDS (65.3%) / 6 TD / 1 INT 78 RUSH YDS / 1 RUSH TD / 26 RUSH YPG
Jayce Brown	WR	19 REC / 216 YDS / 2 TD / 72 YPG
Jaron Tibbs	WR	12 REC / 151 YDS / 2 TD / 50.3 YPG
DeVon Rice	RB	77 YDS / 2 TD / 25.7 YPG / 4.3 YPC 2 REC / 27 REC YDS / 0 REC TD / 13.5 REC YPG
Tobi Osunsanmi	DL	9 TKL / 4 TFL / 3 SACK
Cody Stufflebean	DL	7 TKL / 1 TFL / 2 SACK
Austin Romaine	LB	17 TKL / 1 TFL
Mar'Quavious Moss	DB	7 TKL / 0 TFL / 1 SACK

Arizona 2025 Key Players

Name	Position	Stats
Noah Fifita	QB	534 YDS (66.7%) / 6 TD / 0 INT -11 RUSH YDS / 1 RUSH TD / -5.5 RUSH YPG
Jayin Whatley	WR	8 REC / 206 YDS / 2 TD / 103 YPG
Quincy Craig	RB	156 YDS / 1 TD / 78 YPG / 10.4 YPC
Ismail Mahdi	RB	74 YDS / 1 TD / 37 YPG / 4.9 YPC 2 REC / 24 REC YDS / 1 REC TD / 12 REC YPG
Chase Kennedy	LB	3 TKL / 1 TFL / 2 SACK
Jay'Vion Cole	DB	6 TKL / 1 TFL / 1 SACK / 1 INT
Dominic Lolesio	DL	5 TKL / 0 TFL / 1 SACK
Malachi Bailey	DL	2 TKL / 0 TFL / 0.5 SACK / 1 INT