2025-26 Women's Second Round Odds: Spreads, Lines for all 16 Games

The Round of 32 in the women's NCAA Tournament is upon us. 

Check out the odds for all 16 games at DraftKings Sportsbook as of March 22. 

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SUNDAY, MARCH 22

No. 8 Oregon vs. No. 1 Texas

Spread: Texas -26.5
Moneyline: Texas -100000, Oregon +5000
O/U: 136.5

No. 7 NC State vs. No. 2 Michigan

Spread: Michigan -13.5
Moneyline: Michigan -1050, NC State +675
O/U: 143.5

No. 7 Texas Tech vs. No. 2 LSU

Spread: LSU -24.5
Moneyline: LSU -10000, TTU +3000
O/U: 145.5

No. 6 Baylor vs. No. 3 Duke

Spread: Duke -12.5
Moneyline: Duke -1000, Baylor +650
O/U: 126.5

No. 6 Washington vs. No. 3 TCU

Spread: TCU -9.5
Moneyline: TCU -520, UW +390
O/U: 125.5

No. 5 Michigan State vs. No. 4 Oklahoma

Spread: Oklahoma -7.5
Moneyline: Oklahoma -325, MSU +260
O/U: 158.5

No. 5 Maryland vs. No. 4 UNC

Spread: UNC -2.5
Moneyline: UNC -148, Maryland +124
O/U: 136.5

No. 5 Ole Miss vs. No. 4 Minnesota

Spread: Minnesota -4.5
Moneyline: Minnesota -198, Ole Miss +164
O/U: 126.5

MONDAY, MARCH 23

No. 9 Syracuse vs. No. 1 UConn

Spread: UConn -36.5
Moneyline: TBD
O/U: 139.5

No. 9 USC vs. No. 1 South Carolina

Spread: South Carolina -22.5
Moneyline: South Carolina -10000, USC +3000
O/U: 131.5

No. 8 Oklahoma State vs. No. 1 UCLA

Spread: UCLA -26.5
Moneyline: UCLA -50000, OK State +4000
O/U: 138.5

No. 10 Virginia vs. No. 2 Iowa

Spread: Iowa -14.5
Moneyline: Iowa -1450, UVA +850
O/U: 135.5

No. 7 Illinois vs. No. 2 Vanderbilt

Spread: Vandy -13.5
Moneyline: Vandy -1000, Illinois +650
O/U: 153.5

No. 6 Notre Dame vs. No. 3 Ohio State

Spread: OSU -6.5
Moneyline: OSU -270, ND +220
O/U: 148.5

No. 6 Alabama vs. No. 3 Louisville

Spread: Louisville -8.5
Moneyline: Louisville -410, Alabama +320
O/U: 131.5

No. 5 Kentucky vs. No. 4 West Virginia

Spread: WVU -3.5
Moneyline: WVU -180, UK +150
O/U: 127.5