2025-26 Women's First Round Odds: Spreads, Lines for all 32 Games

The women's path to cutting down the final net begins this weekend.

The women's NCAA Tournament begins Friday and carries into Monday. Let's check out the odds for each first-round game at DraftKings Sportsbook as of March 22.

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FRIDAY, MARCH 20

No. 16 Missouri State 45, No. 1 Texas 87

Spread: Texas -44.5 (Missouri State covers)
O/U: 134.5 (Under hits)

No. 15 Jacksonville 58, No. 2 LSU 116

Spread: LSU -51.5 (LSU covers)
O/U: 162.5 (Over hits)

No. 15 Holy Cross 48, No. 2 Michigan 83

Spread: Michigan -41.5 (Holy Cross covers)
O/U: 130.5 (Over hits)

No. 14 UC San Diego 40, No. 3 TCU 86

Spread: TCU -34.5 (TCU covers)
O/U: 130.5 (Under hits)

No. 14 Charleston 64, No. 3 Duke 81

Spread: Duke -34.5 (Charleston covers)
O/U: 131.5 (Over hits)

No. 13 Western Illinois 51, No. 4 UNC 82

Spread: UNC -25.5 (UNC covers)
O/U: 132.5 (Over hits)

No. 13 Green Bay 58, No. 4 Minnesota 75

Spread: Minnesota -21.5 (Green Bay covers)
O/U: 123.5 (Over hits)

No. 13 Idaho 59, No. 4 Oklahoma 89

Spread: Oklahoma -34.5 (Idaho covers)
O/U: 158.5 (Under hits)

No. 12 Murray State 67, No. 5 Maryland 99

Spread: Maryland -30.5 (Maryland covers)
O/U: 165.5 (Over hits)

No. 12 Gonzaga 66, No. 5 Ole Miss 81

Spread: Ole Miss -14.5 (Ole Miss covers)
O/U: 135.5 (Over hits)

No. 12 Colorado State 62, No. 5 Michigan State 65

Spread: Michigan State -18.5 (CSU covers)
O/U: 133.5 (Under hits)

No. 11 South Dakota State 54, No. 6 Washington 72

Spread: Washington -5.5 (UW covers)
O/U: 131.5 (Under hits)

No. 11 Nebraska 62, No. 6 Baylor 67

Spread: Nebraska -1.5 (Baylor covers)
O/U: 139.5 (Under hits)

No. 10 Tennessee 61, No. 7 NC State 76

Spread: NC State -1.5 (NC State covers)
O/U: 151.5 (Under hits)

No. 10 Villanova 52, No. 7 Texas Tech 57

Spread: Texas Tech -1.5 (TTU covers)
O/U: 129.5 (Under hits)

No. 9 Virginia Tech 60, No. 8 Oregon 70

Spread: Oregon -3.5 (Oregon covers)
O/U: 138.5 (Under hits)

SATURDAY, MARCH 21

No. 16 Southern 34, No. 1 South Carolina 103

Spread: South Carolina -53.5 (SC covers)
O/U: 129.5 (Over hits)

No. 16 UTSA 52, No. 1 UConn 90

Spread: UConn -55.5 (UTSA covers)
O/U: 124.5 (Over hits)

No. 16 Cal Baptist 43, No. 1 UCLA 96

Spread: UCLA -51.5 (UCLA covers)
O/U: 146.5 (Under hits)

No. 15 High Point 61, No. 2 Vanderbilt 102

Spread: Vanderbilt -36.5 (Vandy covers)
O/U: 148.5 (Over hits)

No. 15 Fairleigh Dickinson 48, No. 2 Iowa 58

Spread: Iowa -31.5 (FDU covers)
O/U: 128.5 (Under hits)

No. 14 Howard 54, No. 3 Ohio State 75

Spread: Ohio State -38.5 (Howard covers)
O/U: 142.5 (Under hits)

No. 14 Vermont 52, No. 3 Louisville 72

Spread: Louisville -26.5 (Vermont covers)
O/U: 121.5 (Over hits)

No. 13 Miami OH 54, No. 4 West Virginia 82

Spread: West Virginia -25.5 (WVU covers)
O/U: 124.5 (Over hits)

No. 12 James Madison 56, No. 5 Kentucky 71

Spread: Kentucky -15.5 (JMU covers)
O/U: 129.5 (Under hits)

No. 11 Fairfield 60, No. 6 Notre Dame 79

Spread: Notre Dame -11.5 (ND covers)
O/U: 138.5 (Over hits)

No. 11 Rhode Island 55, No. 6 Alabama 68

Spread: Alabama -9.5 (Alabama covers)
O/U: 120.5 (Over hits)

No. 10 Colorado 57, No. 7 Illinois 66

Spread: Illinois -3.5 (Illinois covers)
O/U: 132.5 (Under hits)

No. 10 Virginia 82, No. 7 Georgia 73

Spread: Georgia -2.5 (UVA covers)
O/U: 131.5 (Over hits)

No. 9 Syracuse 72, No. 8 Iowa State 63

Spread: Iowa State -7.5 (Syracuse covers)
O/U: 149.5 (Under hits)

No. 9 Princeton 68, No. 8 Oklahoma State 82

Spread: OKlahoma State -6.5 (OK State covers)
O/U: 136.5 (Over hits)

No. 9 USC 71, No. 8 Clemson 67 (OT)

Spread: USC -5.5 (Clemson covers)
O/U: 120.5 (Over hits)