National Football League
NFL odds: How to bet Buccaneers vs. Eagles, point spread, more
National Football League

NFL odds: How to bet Buccaneers vs. Eagles, point spread, more

Updated Oct. 14, 2021 5:07 p.m. ET

Tom Brady is closing in on another career milestone as his Tampa Bay Buccaneers face Jalen Hurts and the Philadelphia Eagles on Thursday Night Football, in a game in which the Bucs are heavy favorites.

To help you place your bets, here are the NFL odds on Bucs versus Eagles, from the point spread to the over/under, plus picks from our gambling experts.

Click here for your full NFL odds for Week 6, and check out the all-new "NFL Odds" section on and the FOX Sports app for everything you need in the sports betting world.


The Bucs are 0-2 against the spread (ATS) and 1-1 straight up (SU) in road games this season while the Eagles are 0-2 ATS (0-2 SU) in home games this season

With four touchdown passes, Brady would become the first quarterback in NFL history to reach 600 career touchdown passes. Drew Brees is second on the career list with 571. Aaron Rodgers is next among active QBs with 422 (fifth).

TB12 is 13-3 all-time on Thursday Night Football and 4-1 against Philadelphia in his career. The Eagles beat Brady's New England Patriots in Super Bowl LII 41-33 in 2018.

Brady is 3-4 ATS and 5-2 SU in seven career starts against the Eagles and is 3-0 ATS and SU in three career starts in Philadelphia.

The Bucs are 0-2 ATS and 1-1 SU in Thursday games with Brady.

Since Brady joined Tampa Bay, the Bucs are 8-5 ATS and 13-0 SU as 6+ point favorites but Brady is 0-4 ATS yet 4-0 SU in his past four games against NFC East opponents.

Meanwhile, Philadelphia QB Jalen Hurts’ combined total of 2,812 passing and rushing yards is the fifth-highest in NFL history by a quarterback through his first nine career games.

If the Eagles want to beat the Bucs, Hurts will need all his weapons. Unfortunately, the Eagles placed tight end Dallas Goedert, who is vaccinated, on the reserve/COVID-19 list Tuesday. Goedert may return after he has two negative tests 24 hours apart.

Goedert is third on the Eagles with 216 receiving yards and is tied for the team lead with two touchdowns. 

Speaking of quarterbacks and touchdowns, FOX Bet is offering a limited time special wager for ALL FOX Bet customers on Thursday night's game. From 5 p.m. ET on Thursday until 8:30 p.m. ET, you can double your money if either team scores a single passing touchdown. That's right – bet up to $10 to win $20 total that either the Bucs or Eagles will pass for a touchdown.

Philadelphia's defensive will also need to step up. The Eagles are led by tackle Javon Hargrave, who is having a monster season. He ranks first among DTs in sacks (six), pash rush win rate (23 percent), pass rush productivity (9.4), tackles for loss (seven), and run stops (17).

The Bucs have held three of their five opponents to 25 points or fewer this season.

The Eagles are 5-1 ATS and 6-0 SU in their past six Thursday games.

Since the start of the 2020 season, the Eagles are 4-1 ATS but 1-4 SU as home underdogs of six or more points.

Let's jump into our favorite bets for tonight, with odds courtesy of FOX Bet.


Point spread: Buccaneers -6.5 (favored to win by more than 6.5 points, otherwise Eagles cover)
Moneyline: Buccaneers -300 favorite to win (bet $10 to win $13.33 total); Eagles +250 underdog to win (bet $10 to win $35 total)
Total scoring over/under: 53 points scored by both teams combined

Pick via FOX Sports Betting Analyst Geoff Schwartz: "I'd target the Miles Sanders' over/under 35.5 yards rushing line in this game. 

"Yes, this number is set low, but for good reason. Tampa Bay has the best rushing defense in the NFL and teams flat-out refuse to rush the ball against them. In their four wins, they've seen a total of 37 rushes for 105 yards from the running back position. In their lone loss, the Rams' Sony Michel went wild, with 67 yards on 20 rushes."

"The Eagles will not be winning this game and with their offensive line injuries, I can't imagine they run often with Sanders. Sanders is averaging just a tad under 10 rushes a game and I'd venture he gets closer to five than 10. The Eagles will focus using Hurts legs and arm as Tampa Bay's pass defense is their weakness."

PICK: Miles Sanders UNDER 35.5 rushing yards against Buccaneers via FOX Bet

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