Betting

How to Bet on College Football Week 1 Including Clemson vs. LSU and Louisville vs. Ole Miss

Published Sep. 4, 2026 3:13 p.m. ET

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College football Week 1 is here, and here are some of the biggest matchups this weekend. Clemson vs. LSU headlines Saturday night, while No. 24 Louisville takes on No. 9 Ole Miss on Sunday in the only matchup this week featuring two Top 25 teams.

Another chapter of this battle between the Tigers takes place in Baton Rogue. All the eyes will be on Lane Kiffin and LSU as he begins his tenure with a roster transformed by the transfer portal.

Dabo Swinney is looking to get the Tigers back into the ACC and national championship conversation with Christopher Vizzina taking over at quarterback,

Then the attention shifts to Kiffin's former program, Ole Miss. The Rebels are led by the dynamic duo of quarterback Trinidad Chambliss and running back Kewan Lacy. The Rebels enter the season with plenty of expectations, after making a deep CFP run last season, but first they have an early-season test. Louisville is looking to prove it belongs among the ACC's best and get a major upset against one of the best in the SEC.

Whether you're taking Clemson to avenge last year's 17-10 loss to LSU, riding with Kiffin and Leavitt in their first game together or looking toward Louisville vs. Ole Miss, Week 1 of college football is covered by your favorite sportsbooks like FanDuel, DraftKings, bet365 and more.

FanDuel

Bet $5, Get $350 in Bet Reset Tokens for 7 Days

Create a FanDuel Sportsbook account.
Place one $5+ real-money wager each day for up to 7 days (must be between 3AM ET and 11:59PM ET).
Earn a Bet Reset Token for each qualifying day—up to 7 total tokens.
Apply your Bet Reset Token when placing a wager to activate protection.
If your wager loses, you’ll receive a refund in Bonus Bets (up to $50 per token).
Refunds are issued within 72 hours after bet settlement as Bonus Bets that expire in 7 days.
Bet Reset Tokens expire 24 hours after being issued.

Week 1 Best Matchups

*Odds may differ each site*

No. 11 LSU vs. Clemson

Team	Spread	Total	Moneyline
Clemson	+10.5 -114	O50.5 -113	+328
LSU	-10.5 -109	U50.5 -110	-453

No. 24 Louisville vs. No. 9 Ole Miss

Team	Spread	Total	Moneyline
Louisville	+6.5 -(110)	O55.5 (-114)	+220
Ole Miss	-6.5 (-113)	U55.5 (-109)	-270

No. 2 Oregon vs. Boise State

Team	Spread	Total	Moneyline
Boise State	+24.5 −110	O51.5 −108	+1200
Oregon	−24.5 −110	U51.5 −112	−2400

DraftKings

Claim the New User Offer No Promo Code Needed

Sign up for a new DraftKings Sportsbook account.
Deposit funds (minimum $5).
Select the New Customer Token.
Place a $5+ cash bet (-500 odds or longer).
You will receive $200 in bonus bets instantly, regardless of the outcome of your qualifying wager.
Works the same on desktop & mobile.

For New Customers only

Who Scores in Clemson vs. LSU?

*Odds may differ each site*

Player	Anytime TD Scorer	First TD Scorer	2+ TDs
Dilin Jones (LSU)	−135	+500	+450
Sam Leavitt (LSU)	−105	+650	+600
Gideon Davidson (CLEM)	+100	+1000	+700
Trey'Dez Green (LSU)	+130	+800	+1000
Chris Johnson (CLEM)	+145	+1200	+1100
Harlem Berry (LSU)	+150	+950	+1100

Caesars Sportsbook

Sign Up and Claim the Caesars Sportsbook Promo Code

Click here. This will take you directly to the Caesars Sportsbook betting app or website, where you can select your state. Make sure promo code FOXDYW is applied.
Select Sign Up and create a new account by entering your personal details, including name, email, address, date of birth, and the last four digits of your SSN.
If prompted, enter promo code FOXDYW to ensure the offer is applied.
Place a $1+ cash wager on any eligible market.
Receive 10 × 100% Profit Boost tokens in your account.
Apply the boosts to wagers (up to $25 each) within 14 days to increase potential winnings.

Who Will Find The Endzone?

*Odds may differ each site*

Player	Anytime TD Scorer	First TD Scorer	2+ TDs
Kewan Lacy (MISS)	−290	+360	+190
Isaac Brown (LOU)	−160	+750	+380
Trinidad Chambliss (MISS)	−105	+750	+600
Keyjuan Brown (LOU)	+105	+1000	+700
Deuce Alexander (MISS)	+155	+1100	+1200

bet365

How to claim bet365 Promo with Bonus Code ‘FOX365’.

Click this "Claim Bonus" button to go directly to bet365.
Select Sign Up and create a new account by entering personal details (name, email, date of birth, address, last 4 digits of SSN).
Enter the bonus code FOX365 when prompted to ensure the offer is locked in.
Make a minimum first deposit of $10 using an accepted payment method (PayPal, debit card, online banking, etc.).
Place your first wager. For the Bet $10, Get $365 offer, place a $10+ real-money bet on any market with odds of -500 or longer; win or lose, you’ll receive $365 in bonus bets once it settles.
Bonus bets are credited within 24 hours of the qualifying wager settling.

BetMGM

How to Sign Up and Claim the BetMGM Sportsbook Bonus Code

Click here. This will take you directly to the BetMGM app or website and automatically apply the promo code.
Select Sign Up and create a new account by entering personal details (name, email, date of birth, address, and last 4 digits of SSN).
When prompted, enter the promo code FOXSPORTS to ensure the offer is applied.
Make your first deposit of at least $10 using an accepted payment method (PayPal, Venmo, debit card, online banking, etc.).
Place your first real-money wager on any eligible sport:
If claiming the $1,500 First Bet Offer → refund is triggered only if the first bet loses.
If claiming the $10/$150 Alt Offer → the bet must win to receive the $150 bonus bets.
Bonus bets are credited to your account within 24 hours once the qualifying bet settles.