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Miami Dolphins vs. San Francisco 49ers - Odds: Sep 20, 2026
Dolphins
0-0
0-0
SEP 20, 8:25PM
0-0
49ers
0-0
MATCHUP
ODDS
MATCHUP ODDS
SPREAD
TO WIN
TOTAL
Miami Dolphins
MIA
+10.5
+445
O 46.5
San Francisco 49ers
SF
-10.5
-606
U 46.5
CHANCE TO WIN
Team to win likelihood based on moneyline
MIA 18%
+445
SF 82%
-606
SPREAD
The 49ers must win by 11 points or more to cover the spread
+10.5
MIA
-10.5
SF
TEAM TO WIN
A bet of $100 would win $545 total if the Dolphins win and a bet of $606 would win $706 total if the 49ers win
+445
MIA
-606
SF
TOTAL
The combined final score of both teams is set at 46.5
-110
OVER 46.5
-110
UNDER 46.5
MATCHUP ODDS
MORE ODDS
SPREAD
TO WIN
TOTAL
Miami Dolphins
MIA
+10.5
+445
O 46.5
San Francisco 49ers
SF
-10.5
-606
U 46.5
FOX FACTS
4
INSIGHT
The 49ers' 109.9 passer rating in the red zone was the highest in the NFL in the 2025 regular season.
INSIGHT
The 49ers' 20 sacks were the fewest in the NFL in the 2025 regular season.
INSIGHT
The Dolphins' 74.2% completion rate in Goal to Go situations was the highest in the NFL in the 2025 regular season.
See More
PLAYER NEWS
PLAYER NEWS
Malik Washington
MIA #6 · WR
Washington is listed as a starting wide receiver on the Dolphins' unofficial depth chart.
Malik Willis
MIA #2 · QB
Willis made just one appearance during the Dolphins' three-game preseason slate.
Jaylen Wright
MIA #5 · RB
Wright is listed as the Dolphins' No. 2 running back on the team's initial depth chart ahead of a Week 1 matchup against the Raiders.
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Miami Dolphins
San Francisco 49ers
EVENT INFO
Levi's Stadium
Santa Clara, CA
Sep 20, 2026