MATCHUP ODDS
SPREAD
TO WIN
TOTAL
Arizona Cardinals
ARI
Los Angeles Chargers
LAC
CHANCE TO WIN
Team to win likelihood based on moneyline
ARI 18%
+428
LAC 82%
-578
SPREAD
The Chargers must win by 11 points or more to cover the spread
+10.5
ARI
-10.5
LAC
TEAM TO WIN
A bet of $100 would win $528 total if the Cardinals win and a bet of $578 would win $678 total if the Chargers win
+428
ARI
-578
LAC
TOTAL
The combined final score of both teams is set at 46.5
-109
OVER 46.5
-111
UNDER 46.5
FOX FACTS
4
INSIGHT
The Cardinals' 617 passing targets were the most in the NFL in the 2025 regular season.
INSIGHT
The Cardinals' 427 receptions were the most in the NFL in the 2025 regular season.
INSIGHT
The Chargers' 10 interceptions in the first half were the most in the NFL in the 2025 regular season.
PLAYER NEWS
James Conner ARI #6 · RB
Cardinals coach Mike LaFleur said Wednesday that it's "too early to tell" if Conner (foot) will be ready for Week 1 against the Chargers, Theo Mackie of The Arizona Republic reports.
Jeremiyah Love ARI #4 · RB
Love (ankle) was spotted doing some light agility work with trainers ahead of Wednesday's practice, Theo Mackie of The Arizona Republic reports.
Trey Benson ARI · RB
Benson (knee) reverted to the Cardinals' injured reserve list Tuesday, David Furones of the South Florida Sun Sentinel reports.
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Arizona Cardinals
Los Angeles Chargers
EVENT INFO
SoFi Stadium
Inglewood, CA
Sep 13, 2026
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