Texans vs. Buccaneers 2025 Prediction, Odds, Picks - Sep 15

The Houston Texans (0-1) are favored by 2.5 points against the Tampa Bay Buccaneers (1-0) on September 15, 2025, starting at 7 p.m. ET, airing on ABC/ESPN. The over/under for this one is set at 42.5 points.

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Texans vs. Buccaneers Odds & Betting Lines

Texans vs. Buccaneers Prediction & Pick

• Pick ATS: Buccaneers (+2.5)
  
• Pick OU: Over (42.5)
  
• Prediction: Buccaneers 26 - Texans 22

How to Watch Houston vs. Tampa Bay

• Game date: Monday, September 15, 2025
• Time: 7 p.m. ET
• Venue: NRG Stadium
• Location: Houston, Texas
• TV: ABC/ESPN
• Live Boxscore: FOX Sports

Texans vs. Buccaneers Recent Matchups

• In their last two head-to-head matchups, Houston has defeated Tampa Bay two times.
• In their last two head-to-head matchups, Houston has compiled 62 points against Tampa Bay, while allowing only 57 points.

Houston Betting Info

• Houston covered seven times in 17 matchups with a spread last season.
• The Texans had two wins ATS (2-5-1) as a 2.5-point favorite or greater last season.
• Last season, the combined scoring went over the point total six times in Houston games.
• The Texans put together a 9-2 record in games they were favored on the moneyline last season (winning 81.8% of those games).
• Houston went 8-2 last year (winning 80% of its games) when it played as a moneyline favorite of -130 or shorter.
• Based on this contest's moneyline, the Texans have an implied win probability of 56.5%.

Texans Stats (2024)

Houston's Key Players

Offense

• C.J. Stroud passed for 3,727 yards last year, with 20 touchdowns and 12 interceptions. He completed 63.2% of his attempts while averaging 219.2 yards per game and 7 per attempt.
• Stroud also rushed for 233 yards.
• Nico Collins had 1,006 receiving yards and seven touchdowns on 68 receptions, while being targeted 99 times.
• Last year, Dalton Schultz caught 53 passes for 532 receiving yards with two touchdowns through the air. He was targeted 85 total times and averaged 3.1 receptions per game over 17 games played.
• Nick Chubb averaged 41.5 rushing yards per game in eight games for the Browns (332 total yards), with three rushing touchdowns.
• Chubb also added five catches (0.6 per game) for 31 yards (3.9 per game) and one receiving touchdown. He was on the receiving end of 11 targets.

Defense

• E.J. Speed intercepted one pass and also had 142 tackles, seven TFL, and five passes defended for the Colts in 2024.
• Danielle Hunter had 46 tackles, 17 TFL, and 12 sacks.
• Will Anderson Jr. had 11 sacks as well as 16 TFL and 37 tackles in the 2024 campaign.
• Henry To'oTo'o totaled 1.5 sacks as well as seven TFL, 104 tackles, and one interception.

Tampa Bay Betting Info

• Tampa Bay put together a 10-7-0 record against the spread last year.
• As 2.5-point underdogs or greater, the Buccaneers went 4-2 against the spread last season.
• Last season, 12 Tampa Bay games hit the over.
• Last season, the Buccaneers won three out of the eight games in which they were the underdog.
• Tampa Bay entered six games last season as the underdog by +110 or more and were 2-4 in those contests.
• The sportsbooks' moneyline implies a 47.6% chance of a victory for the Buccaneers.

Buccaneers Stats (2024)

Tampa Bay's Key Players

Offense

• Baker Mayfield threw for 4,500 yards last year (third in the NFL), with 41 TDs (second in the NFL) and 16 interceptions. He completed 71.4% of his attempts, averaging 264.7 yards per game and 7.9 per attempt.
• Mayfield also rushed for three TDs and 378 yards.
• Bucky Irving had 1,122 yards rushing (10th in the NFL) and eight rushing TDs, averaging 66 yards per game and 5.4 per attempt (sixth in NFL).
• Irving added 47 catches (2.8 per game) for 392 yards (23.1 per game), without a receiving touchdown. He was targeted 52 times.
• In 14 games last year, Mike Evans had 74 catches (5.3 per game on 7.9 targets per game) for 1,004 yards and 11 TDs (fourth in NFL).
• Rachaad White scored three TDs on the ground, while running for 613 total yards (4.3 per carry and 40.9 per game).
• White also had 393 receiving yards (26.2 per game) on 51 catches (3.4 per game). He was targeted 57 times and caught six TD passes.

Defense

• In 2024, Lavonte David had 122 tackles, nine TFL, 5.5 sacks, and one interception in 17 games.
• YaYa Diaby totaled 4.5 sacks to go along with his 13 TFL and 54 tackles over 16 games.
• Zyon McCollum had 82 tackles, one TFL, and two interceptions in 2024.
• Calijah Kancey's production included 28 tackles, 11 TFL, and 7.5 sacks in 12 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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