Chiefs vs. Raiders 2025 Prediction, Odds, Picks - Oct 19

Updated Oct. 19, 2025 12:43 p.m. ET

Data Skrive

The Kansas City Chiefs (3-3) are heavy favorites (-12.5) versus the Las Vegas Raiders (2-4) in a battle of two division rivals. An over/under of 45.5 points has been established for the matchup.

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Chiefs vs. Raiders Odds & Betting Lines

Chiefs vs Raiders Betting Information updated as of October 19, 2025, 12:33 p.m. ET.
Favorite	Spread	Favorite Spread Odds	Underdog Spread Odds	Total	Over Total Odds	Under Total Odds
Chiefs	-12.5	-121	-110	45.5	-107	-125

Chiefs vs. Raiders Prediction & Pick

Pick ATS: Chiefs (-12.5)
Pick OU: Under (45.5)
Prediction: Chiefs 29 - Raiders 16

How to Watch Kansas City vs. Las Vegas

Game date: Sunday, October 19, 2025
Time: 1 p.m. ET
Venue: GEHA Field at Arrowhead Stadium
Location: Kansas City, Missouri
TV: CBS
Live Boxscore: FOX Sports

Chiefs vs. Raiders Recent Matchups

Over their last five meetings, Kansas City has totaled four wins versus Las Vegas.
Las Vegas has been outscored by 35 points in its last five tilts versus Kansas City.

Kansas City Betting Info

Against the spread, Kansas City is 3-3-0 this season.
Kansas City games this year have hit the over on three of six set point totals (50%).
When playing as moneyline favorites, the Chiefs have won 50% of the time (2-2).
The Chiefs have an implied win probability, based on the moneyline, of 90.5%.

Chiefs Stats

Stat	Average (Total)	Rank
Pass yards	241.3 (1,448)	8
Rush yards	118.7 (712)	14
Points scored	25.8 (155)	8
Pass yards against	192 (1,152)	8
Rush yards against	119.2 (715)	19
Points allowed	20.7 (124)	11

Kansas City's Key Players

Offense

Patrick Mahomes has thrown for 1,514 yards (sixth in the NFL), 11 touchdowns (sixth in the NFL) and two interceptions this year. He averages 252.3 yards per game and 7.1 per attempt, while completing 64.8% of his attempts.
He has tacked on 222 rushing yards (37 per game) and four touchdowns on the ground.
Marquise Brown's 302 receiving yards this season have come from 44 targets and 30 receptions. He's averaging 50.3 receiving yards and five catches per game, with three receiving touchdowns.
In the passing game, Tyquan Thornton, has racked up 272 receiving yards and three touchdowns after hauling in 13 balls on 25 targets. Per game, he's averaging 54.4 yards and 2.6 receptions over five games.
Travis Kelce has put up 321 receiving yards and two touchdowns with 28 catches on 37 targets. He is averaging 4.7 receptions and 53.5 yards per game.

Defense

On defense for the Chiefs, Nick Bolton has put up 53 tackles and four TFL in 2025.
George Karlaftis III has 22 tackles, six TFL, 3.5 sacks, and one pass defended.
Chamarri Conner has totaled 45 tackles this year.
This season, Drue Tranquill has 30 tackles, four TFL, and two sacks. He's third on the Chiefs in tackles.

Las Vegas Betting Info

Las Vegas has covered the spread two times in six games with a set total.
Games involving Las Vegas have hit the over twice this year.
The Raiders have been underdogs in four games this season and won one (25%) of those contests.
Oddsmakers have implied with the moneyline set for this matchup that the Raiders have a 13.8% chance to win.

Raiders Stats

Stat	Average (Total)	Rank
Pass yards	201.5 (1,209)	19
Rush yards	105.2 (631)	23
Points scored	17.2 (103)	29
Pass yards against	215.7 (1,294)	19
Rush yards against	95.3 (572)	10
Points allowed	24.8 (149)	23

Las Vegas' Key Players

Offense

Ashton Jeanty has rushed for three touchdowns this year, and has accumulated 424 total rushing yards (70.7 per game and 4 per carry).
On top of his impact on the ground, Jeanty has caught 14 passes (on 19 targets) for 73 yards (sixth on the Raiders), with two receiving touchdowns. He's averaging 12.2 yards per game.
Through six games, Geno Smith has 1,350 passing yards, while throwing seven touchdowns against 10 interceptions and completing 66.1% of his passes.
He has also added 71 rushing yards (third on the Raiders), while scoring zero touchdowns on the ground (averaging 11.8 yards per game and 3.6 per carry).
Tre Tucker has registered 356 receiving yards and four touchdowns (seventh in the NFL) on 24 receptions, while being targeted 33 times on the season.
Jakobi Meyers has 329 receiving yards from 29 receptions after getting 43 targets.

Defense

Maxx Crosby has intercepted one pass and also has 25 tackles, 10 TFL, four sacks, and five passes defended in 2025.
Devin White's stats include one interception as well as 48 tackles, six TFL, one sack, and two passes defended.
Jeremy Chinn has 38 tackles, two TFL, and two passes defended during the 2025 season.
Jonah Laulu has 16 tackles, six TFL, four sacks, and two passes defended.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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