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The Week 12 NFL slate has plenty of exciting matchups on the docket. Among those games is the Detroit Lions taking on the Indianapolis Colts.
If you're seeking additional betting info for Week 12 in the NFL, we have you covered with betting odds for all the important matchups.
Check out the full NFL football schedule on FOX Sports!
Week 12 Betting Lines & Game Info
Cleveland Browns vs. Pittsburgh Steelers
Odds & Prediction
- Spread: Steelers (-3.5)
- Moneyline: Steelers -205, Browns +171
- Total: 36.5 points
- Prediction: Steelers 28, Browns 12
How to Watch
- Game Date: Thursday, Nov. 21
- Game Time: 8:15 p.m. ET
- TV Channel: Amazon Prime Video
- Location: Cleveland, Ohio
Chicago Bears vs. Minnesota Vikings
Odds & Prediction
- Spread: Vikings (-3)
- Moneyline: Vikings -168, Bears +141
- Total: 39.5 points
- Prediction: Vikings 25, Bears 15
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 1 p.m. ET
- TV Channel: Watch Online: FOX
- Location: Chicago, Illinois
Miami Dolphins vs. New England Patriots
Odds & Prediction
- Spread: Dolphins (-7.5)
- Moneyline: Dolphins -382, Patriots +301
- Total: 45.5 points
- Prediction: Dolphins 23, Patriots 17
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 1 p.m. ET
- TV Channel: CBS
- Location: Miami Gardens, Florida
Houston Texans vs. Tennessee Titans
Odds & Prediction
- Spread: Texans (-7.5)
- Moneyline: Texans -415, Titans +322
- Total: 40.5 points
- Prediction: Texans 30, Titans 14
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 1 p.m. ET
- TV Channel: CBS
- Location: Houston, Texas
New York Giants vs. Tampa Bay Buccaneers
Odds & Prediction
- Spread: Buccaneers (-6)
- Moneyline: Buccaneers -278, Giants +225
- Total: 40.5 points
- Prediction: Buccaneers 29, Giants 17
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 1 p.m. ET
- TV Channel: CBS
- Location: East Rutherford, New Jersey
Carolina Panthers vs. Kansas City Chiefs
Odds & Prediction
- Spread: Chiefs (-10.5)
- Moneyline: Chiefs -662, Panthers +475
- Total: 43 points
- Prediction: Chiefs 33, Panthers 13
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 1 p.m. ET
- TV Channel: CBS
- Location: Charlotte, North Carolina
Washington Commanders vs. Dallas Cowboys
Odds & Prediction
- Spread: Commanders (-10.5)
- Moneyline: Commanders -625, Cowboys +451
- Total: 44.5 points
- Prediction: Commanders 34, Cowboys 16
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 1 p.m. ET
- TV Channel: Watch Online: FOX
- Location: Landover, Maryland
Indianapolis Colts vs. Detroit Lions
Odds & Prediction
- Spread: Lions (-7.5)
- Moneyline: Lions -368, Colts +289
- Total: 50.5 points
- Prediction: Lions 30, Colts 18
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 1 p.m. ET
- TV Channel: Watch Online: FOX
- Location: Indianapolis, Indiana
Las Vegas Raiders vs. Denver Broncos
Odds & Prediction
- Spread: Broncos (-5.5)
- Moneyline: Broncos -259, Raiders +209
- Total: 41.5 points
- Prediction: Broncos 27, Raiders 16
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 4:05 p.m. ET
- TV Channel: CBS
- Location: Paradise, Nevada
Seattle Seahawks vs. Arizona Cardinals
Odds & Prediction
- Spread: Cardinals (-1)
- Moneyline: Cardinals -118, Seahawks -102
- Total: 47 points
- Prediction: Cardinals 25, Seahawks 22
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 4:25 p.m. ET
- TV Channel: Watch Online: FOX
- Location: Seattle, Washington
Green Bay Packers vs. San Francisco 49ers
Odds & Prediction
- Spread: Packers (-6.5)
- Moneyline: Packers -292, 49ers +236
- Total: 44.5 points
- Prediction: Packers 28, 49ers 19
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 4:25 p.m. ET
- TV Channel: Watch Online: FOX
- Location: Green Bay, Wisconsin
Los Angeles Rams vs. Philadelphia Eagles
Odds & Prediction
- Spread: Eagles (-3)
- Moneyline: Eagles -161, Rams +135
- Total: 49 points
- Prediction: Eagles 24, Rams 20
How to Watch
- Game Date: Sunday, Nov. 24
- Game Time: 8:20 p.m. ET
- TV Channel: NBC
- Location: Inglewood, California
Los Angeles Chargers vs. Baltimore Ravens
Odds & Prediction
- Spread: Ravens (-3)
- Moneyline: Ravens -162, Chargers +137
- Total: 50.5 points
- Prediction: Chargers 24, Ravens 22
How to Watch
- Game Date: Monday, Nov. 25
- Game Time: 8:15 p.m. ET
- TV Channel: ESPN
- Location: Inglewood, California
Learn more about today's games on FOX Sports.
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