Pirates vs. Guardians Prediction, Odds, Picks - April 20

Bo Naylor and the Cleveland Guardians hit the field against Isiah Kiner-Falefa and the Pittsburgh Pirates at PNC Park on Sunday at 1:35 p.m. ET. The Guardians are -101 moneyline underdogs in this matchup against the favored Pirates (-119). Cleveland is the favorite on the run line (-1.5). The total is 8 runs for the matchup (with -116 odds on the over and -104 odds on the under).

Check out everything you need to know from a betting perspective on the Pirates-Guardians game, regarding the run line, moneyline and total, plus expert picks.

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Guardians vs. Pirates Highlights | MLB on FOX

Check out the best highlights between the Cleveland Guardians and the Pittsburgh Pirates.

Pirates vs. Guardians Game Information & Odds

• When: Sunday, April 20, 2025 at 1:35 p.m. ET
• Where: PNC Park in Pittsburgh, Pennsylvania
• How to watch on TV: SportsNet PT and CLEG

Pirates vs. Guardians Prediction

• Score Prediction: Pirates 5, Guardians 4
• Total Prediction: Over 8 runs
• Win Probabilities: Pirates 52%, Guardians 48%

Pirates vs. Guardians Betting Insights

• This season, the Pirates have been favored 10 times and won five of those games.
• Pittsburgh has entered eight games this season favored by -119 or more and is 3-5 in those contests.
• Bookmakers have implied with the moneyline set for this matchup that the Pirates have a 54.3% chance to win.
• The Guardians have been chosen as underdogs in 11 games this year and have walked away with the win four times (36.4%) in those games.
• Cleveland has a win-loss record of 3-6 when favored by -101 or worse by sportsbooks this year.
• The Guardians have an implied victory probability of 50.2% according to the moneyline set by oddsmakers for this matchup.

Pirates Recent Betting Performance

• The Pirates played as the moneyline favorite in five of their last 10 games, and they finished 3-2 in those matchups.
• Over their last 10 matchups, the Pirates and their opponents combined to hit the over two times (all 10 of the games had set totals).
• The Pirates have put together a 3-7-0 record against the spread over their past 10 games.

Pirates Recent Stats

Pirates Player Insights

• Oneil Cruz paces the Pirates in home runs (five) and runs batted in (11).
• Among all batters in baseball, Cruz is 22nd in homers and 58th in RBI.
• Cruz brings a hitting streak of four games into this game. During his last five outings he is batting .278 with three home runs, three walks and six RBI.
• Kiner-Falefa's .269 batting average paces his team.
• Kiner-Falefa is 260th in home runs in MLB, and 209th in RBI.
• Kiner-Falefa carries a three-game streak with at least one hit into this matchup. In his last five games he is batting .294 with a double and an RBI.
• Enmanuel Valdez is hitting .239 with three doubles, two triples, a home run and seven walks.
• Valdez has at least one base hit in four straight games. During his last five outings he is hitting .294 with a triple, a home run, three walks and three RBI.
• Ke'Bryan Hayes is hitting .197 with a double, a triple, a home run and seven walks.

Pirates Team Props

Guardians Recent Betting Performance

• In five games as underdogs over the last 10 matchups, the Guardians have a record of 2-3.
• In their last 10 games with a total, the Guardians and their opponents are 4-4-2 when it comes to hitting the over.
• The Guardians have six wins against the spread in their last 10 chances.

Guardians Recent Stats

Guardians Player Insights

• Steven Kwan paces the Guardians with a team-high batting average of .329.
• Kwan's home run total places him 65th in the majors, and he is 40th in RBI.
• Kwan takes a hitting streak of three games into this game. In his last five games he is hitting .350 with a double, a home run, two walks and four RBI.
• Jose Ramirez is hitting .269 with four doubles, four home runs and seven walks.
• Ramirez is currently 38th in homers and 97th in RBI in the major leagues.
• Kyle Manzardo has been solid source of run production for the Guardians with five long balls and 13 runs batted in.
• Carlos Santana is batting .247 with two doubles, two home runs and eight walks.

Guardians Team Props

Guardians vs. Pirates Highlights | MLB on FOX

Check out the best highlights between the Cleveland Guardians and the Pittsburgh Pirates.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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Pittsburgh Pirates

Cleveland Guardians