Padres vs. Cardinals Prediction, Odds, Picks - August 2

The St. Louis Cardinals and Brendan Donovan hit the field at PETCO Park against Manny Machado and the San Diego Padres on Saturday. The Cardinals have been listed as +156 moneyline underdogs for this matchup against the Padres (-188). San Diego (-1.5) is the favorite on the run line. An 8-run total is set in the matchup.

Take a look at everything you need from a betting perspective on the Padres-Cardinals game, regarding the run line, moneyline and total, plus expert picks.

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Padres vs. Cardinals Game Information & Odds

• When: Saturday, August 2, 2025 at 10:10 p.m. ET
• Where: PETCO Park in San Diego, California
• How to watch on TV: SDPA and FDSMW

Padres vs. Cardinals Prediction

• Score Prediction: Padres 4, Cardinals 3
• Total Prediction: Under 8 runs
• Win Probabilities: Padres 55%, Cardinals 45%

Padres vs. Cardinals Betting Insights

• The Padres have entered the game as favorites 57 times this season and won 34, or 59.6%, of those games.
• San Diego is 8-4 this season when entering a game favored by -188 or more on the moneyline.
• The moneyline for this contest implies a 65.3% chance of a victory for the Padres.
• The Cardinals have been underdogs in 56 games this season and have come away with the win 27 times (48.2%) in those contests.
• This season, St. Louis has been victorious one time in six chances when named as an underdog of at least +156 or worse on the moneyline.
• Bookmakers have implied with the moneyline set for this matchup that the Cardinals have a 39.1% chance of pulling out a win.

Padres Recent Betting Performance

• The Padres were the moneyline favorite in five of their last 10 games, and went 3-2 in those matchups.
• Over their last 10 matchups -- all had a set run total -- the Padres and their opponents combined to go over the total three times.
• The Padres have put together a 6-4-0 record against the spread over their past 10 games.

Padres Recent Stats

Padres Player Insights

• Machado has racked up a team-high batting average of .302, and paces the Padres in home runs (20) and runs batted in (71).
• Among all MLB hitters, Machado ranks eighth in batting average, 29th in on-base percentage, and 16th in slugging.
• Machado carries a nine-game hitting streak into this matchup. In his last 10 games he is hitting .452 with four doubles, two home runs and 11 RBIs.
• Fernando Tatis Jr. is batting .267 with 18 doubles, two triples, 17 home runs and 61 walks.
• Tatis ranks 55th in home runs and 108th in RBI in the majors.
• Luis Arraez is batting .297 with 20 doubles, four triples, six home runs and 22 walks.
• Arraez is on a 14-game hitting streak entering this contest. In his last 10 outings he is hitting .425 with three doubles, a home run, three walks and five RBIs.
• Xander Bogaerts has 24 doubles, seven home runs and 44 walks while batting .267.
• Bogaerts is riding a two-game hitting streak into this one. During his last five outings he is hitting .273 with a double, a home run, a walk and two RBIs.

Padres Team Props

Cardinals Recent Betting Performance

• Over the past 10 games, the Cardinals have been underdogs twice and split those games 1-1.
• When it comes to hitting the over, the Cardinals and their opponents are 2-6-2 in their last 10 games with a total.
• The Cardinals have won three of their last 10 games against the spread.

Cardinals Recent Stats

Cardinals Player Insights

• Donovan has 24 doubles, nine home runs and 39 walks while batting .282.
• In all of the majors, Donovan is 156th in home runs and 129th in RBI.
• Alec Burleson has a club-best .284 batting average.
• Burleson is currently 89th in home runs and 83rd in RBI in the major leagues.
• Willson Contreras has been solid source of run production for the Cardinals with 15 long balls and 62 runs batted in.
• Masyn Winn has 23 doubles, seven home runs and 27 walks while hitting .271.

Cardinals Team Props

Cardinals vs. Padres Highlights | MLB on FOX

Check out the best moments between the St. Louis Cardinals and San Diego Padres.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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