Blue Jays vs. Giants Prediction, Odds, Picks - July 18

Vladimir Guerrero Jr. and the Toronto Blue Jays take on Jung Hoo Lee and the San Francisco Giants on Friday at 7:07 p.m. ET in the first game of a three-game series. Oddsmakers list the Blue Jays as -144 favorites on the moneyline, while giving the underdog Giants +121 moneyline odds to win. Toronto (-1.5) is the favorite on the run line. The over/under is 8.5 runs for this game.

Here is everything you need to know from a betting perspective on the Blue Jays-Giants game, regarding the run line, moneyline and total, plus expert picks.

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Blue Jays vs. Giants Game Information & Odds

• When: Friday, July 18, 2025 at 7:07 p.m. ET
• Where: Rogers Centre in Toronto, Ontario
• How to watch on TV: MLB Network, SNET, and NBCS-BA

Blue Jays vs. Giants Prediction

• Score Prediction: Blue Jays 5, Giants 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Blue Jays 54%, Giants 46%

Blue Jays vs. Giants Betting Insights

• The Blue Jays have been favorites in 42 games this season and won 25 (59.5%) of those contests.
• Toronto is 16-6 this season when entering a game favored by -144 or more on the moneyline.
• The bookmakers' moneyline implies a 59% chance of a victory for the Blue Jays.
• The Giants have been underdogs in 36 games this season and have come away with the win 18 times (50%) in those contests.
• San Francisco has a mark of 5-7 in contests where oddsmakers favor it by +121 or worse on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Giants have a 45.2% chance of pulling out a win.

Blue Jays Recent Betting Performance

• The Blue Jays went 6-3 across the nine games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings (all had set totals), the Blue Jays combined with their opponents to hit the over on the total three times.
• The Blue Jays' record against the spread is 3-7-0 over their past 10 games.

Blue Jays Recent Stats

Blue Jays Player Insights

• Guerrero is hitting .277 with 19 doubles, 12 home runs and 56 walks.
• Of all batters in MLB, Guerrero ranks 82nd in homers and 72nd in RBI.
• George Springer has put his power on display as he paces his team with 16 home runs and 53 runs batted in.
• Of all MLB hitters, Springer is 43rd in home runs and 43rd in RBI.
• Bo Bichette has racked up a team-best 53 runs batted in.
• Bichette will look to build on his nine-game hitting in this game. In his last 10 games he is hitting .378 with five doubles, a home run, four walks and four RBIs.
• Alejandro Kirk's .303 batting average leads his team.

Blue Jays Team Props

Giants Recent Betting Performance

• The Giants have played as underdogs in five of their past 10 games and won two of those contests.
• In their last 10 games with a total, the Giants and their opponents are 4-5-1 when it comes to hitting the over.
• The Giants have a record of 5-5-0 ATS over their last 10 games.

Giants Recent Stats

Giants Player Insights

• Rafael Devers leads the Giants with 17 long balls and runs batted in, driving in 68.
• Devers is 31st in homers and 10th in RBI among all hitters in MLB.
• Lee has 19 doubles, eight triples, six home runs and 32 walks while batting .249.
• Lee is currently 201st in homers and 97th in RBI in the big leagues.
• Heliot Ramos has accumulated a team-high batting average of .262.
• Willy Adames is batting .220 with 14 doubles, two triples, 12 home runs and 45 walks.

Giants Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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