Colorado vs. Delaware Prediction, Odds, Picks - September 6, 2025

Updated Sep. 6, 2025 3:04 p.m. ET

FOX Sports

The Delaware Fightin' Blue Hens (1-0) are facing tough odds as 23.5-point underdogs heading into their matchup on Saturday, September 6, 2025 against the Colorado Buffaloes (0-1). The over/under is set at 49.5 points for the game.

Facing the Georgia Tech Yellow Jackets in their most recent contest, the Buffaloes lost 27-20. The Fightin' Blue Hens' most recent contest was versus the Delaware State Hornets, and they won by a score of 35-17.

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Colorado vs. Delaware Game Information & Odds

When: Saturday, September 6, 2025 at 3:30 p.m. ET
Location: Folsom Field in Boulder, Colorado
TV: FOX
Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)

Colorado vs Delaware Betting Information updated as of September 6, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Colorado	-23.5 (-115)	-2500	+1170	49.5	-111	-109

Colorado vs. Delaware Prediction

Predictions are made by the Data Skrive betting model.

Learn more about the Colorado Buffaloes vs. the Delaware Fightin' Blue Hens game on FOX Sports!

Colorado vs. Delaware Betting Insights

Per the spread and over/under, the implied score for the game is Buffaloes 36, Fightin' Blue Hens 13.
The Buffaloes have a 96.2% chance to claim victory in this contest based on the moneyline's implied probability. The Fightin' Blue Hens have a 7.9% implied probability.
Colorado has not won against the spread this season in one games with a spread.
Delaware has compiled a 0-1-0 record against the spread this season.

Colorado vs. Delaware: 2025 Stats Comparison

	Colorado	Delaware
Off. Points per Game (Rank)	20 (91)	35 (52)
Def. Points per Game (Rank)	27 (94)	17 (66)
Turnovers Allowed (Rank)	0 (1)	1 (55)
Turnovers Forced (Rank)	3 (8)	2 (22)

Colorado 2025 Key Players

Name	Position	Stats
Kaidon Salter	QB	159 YDS (60.7%) / 1 TD / 0 INT 43 RUSH YDS / 1 RUSH TD / 43.0 RUSH YPG
Dekalon Taylor	RB	2 YDS / 0 TD / 2.0 YPG / 2.0 YPC 3 REC / 38 REC YDS / 1 REC TD / 38.0 REC YPG
Micah Welch	RB	64 YDS / 0 TD / 64.0 YPG / 5.8 YPC
Omarion Miller	WR	1 REC / 39 YDS / 0 TD / 39.0 YPG
Martavius French	LB	5 TKL / 1.0 TFL
Reginald Hughes	LB	13 TKL / 0.0 TFL
D.J. McKinney	DB	4 TKL / 0.0 TFL / 1 INT / 1 PD
Quency Wiggins	DL	2 TKL / 1.0 TFL / 1.0 SACK

Delaware 2025 Key Players

Name	Position	Stats
Nick Minicucci	QB	270 YDS (77.8%) / 3 TD / 0 INT 44 RUSH YDS / 1 RUSH TD / 44.0 RUSH YPG
Kyre Duplessis	WR	7 REC / 89 YDS / 1 TD / 89.0 YPG
Jake Thaw	WR	7 REC / 92 YDS / 1 TD / 92.0 YPG
Ja'Carree Kelly	WR	2 REC / 22 YDS / 1 TD / 22.0 YPG
Dillon Trainer	LB	6 TKL / 3.0 TFL / 1.0 SACK
Gavin Moul	LB	9 TKL / 2.0 TFL
KT Seay	DB	4 TKL / 0.0 TFL / 1 INT / 1 PD
Anthony Crenshaw	LB	8 TKL / 0.0 TFL