Rooney spent 13 years at Old Trafford and became United's all-time top scorer while winning five English Premier League titles, the Champions League in 2008, and the FA Cup in 2016.
The matches take place in early March.
Sheffield Wednesday vs. Manchester City
Reading or Cardiff vs. Sheffield United
Chelsea vs. Shrewsbury or Liverpool
West Bromwich Albion vs. Newcastle or Oxford
Leicester vs. Coventry or Birmingham
Northampton or Derby vs. Manchester United
Southampton or Tottenham vs. Norwich
Portsmouth vs. Arsenal