Quinton Rose added 16 points, six rebounds and six assists, Nate Pierre-Louis scored 16 and Ernest Aflakpui 10. The Owls (4-0) built a 16-0 lead in the first 3½ minutes and mostly kept the lead in double digits the rest of the way.
The Greyhounds (1-3) had a 9-2 run to cut the deficit to 30-24 in the first half but that was as close as they would get. Temple pushed the lead back to 45-33 by halftime and kept their advantage between nine and 18 in the second half.
Temple committed just eight turnovers to Loyola's 22.