Andy Isabella - NFL News, Rumors, & Updates

Gets cut San Francisco waived Isabella (ankle) with a failure to disclose physical condition designation Tuesday, Aaron Wilson of KPRC 2 Houston reports.

Impact It wasn't a full week after Isabella signed with the 49ers before he suffered an ankle injury, per Matt Barrows of The Athletic, and he's now getting waived. In a corresponding transaction, San Francisco signed wide receiver Equanimeous St. Brown on Tuesday.

AUGUST 5, 2025 • ROTOWIRE

Exits practice Monday Isabella had to leave practice Monday with an undisclosed injury, Nick Wagoner of ESPN.com reports.

Impact The wide receiver signed with the 49ers on Thursday with the possibility of competing for a depth spot in a crowded receiver room. At the same time, Isabella was not able to elevate from Pittsburgh's practice squad in 2024, got cut by the Bills before last season and last caught an NFL pass in 2022 with the Cardinals. Any missed time will not help him compete for a roster spot.

AUGUST 5, 2025 • ROTOWIRE

Signs with San Francisco The 49ers signed Isabella to a one-year contract Thursday, Jennifer Lee Chan of NBC Sports Bay Area reports.

Impact Isabella hasn't caught a regular-season pass since the 2022 season with the Cardinals, the team that selected him in the second round of the 2019 Draft. Isabella spent time in the UFL with the St. Louis Battlehawks earlier this year. He should be viewed as a long shot to make the Niners' 53-man roster.

JULY 31, 2025 • ROTOWIRE

Cut from Steelers' practice squad Isabella was let go from the Steelers' practice squad Tuesday, Teresa Varley of the team's official site reports.

Impact Isabella spent the first two months of the regular season without a team after failing to make the Bills' 53-man roster at the end of training camp. He managed to catch on with the Steelers' practice squad Oct. 25, but he was not elevated for a game. Assuming he clears waivers, Isabella will look to join a team in need of depth at wide receiver.

NOVEMBER 5, 2024 • ROTOWIRE

Joins Pittsburgh's practice squad The Steelers signed Isabella to the practice squad Friday.

Impact Isabella, who spent time with the Bills during the offseason, will now get a chance to operate in an emergency depth role for Pittsburgh. The 2019 second-round pick has appeared in four combined regular-season games with Buffalo over the last two years.

OCTOBER 25, 2024 • ROTOWIRE

Cut by Buffalo The Bills released Isabella on Tuesday, Alaina Getzenberg of ESPN.com reports.

Impact Selected with the No. 62 overall pick in the 2019 NFL Draft by the Cardinals, Isabella was cut by Arizona in October of 2022 and has spent the last couple years bouncing around the practice squads and active rosters of the Ravens and Bills. Now 27, Isabella is running out of time in the NFL and hasn't caught a regular-season pass since he left the Cardinals.

AUGUST 27, 2024 • ROTOWIRE

Recovers from injury Isabella (leg) returned to practice Wednesday, Joe Buscaglia of The Athletic reports.

Impact Isabella was able to make a quick recovery after being carted off the field Monday. The 27-year-old is likely facing an uphill battle to make the Bills' final 53-man roster, but his speedy return to the field should keep him in contention for now.

AUGUST 7, 2024 • ROTOWIRE

Carted off during camp Isabella (leg) left Monday's camp session on a cart, Matt Parrino of The Syracuse Post-Standard reports.

Impact The 2019 second-round pick out of UMass is fighting for a depth spot on Buffalo's 53-man roster after appearing in just four regular-season games in 2023. The severity of Isabella's injury is currently unknown, and if the 27-year-old misses time, his chances of making it past the Bills' final roster cuts are likely slim.

AUGUST 5, 2024 • ROTOWIRE

Andy Isabella, Buffalo Bills, Wide Receiver Andy Isabella is a 5-10, 175-pound Athlete from Cleveland, OH.

APRIL 12, 2024 • 247SPORTS.COM

Practice squad bound Isabella was reverted back to the Bills' practice squad Friday, per the NFL's transaction log.

Impact The 2019 second-round pick was promoted to Buffalo's active roster ahead of the team's Thursday night affair, but he's since been reverted back to the practice squad. Isabella has recorded 33 receptions for 447 yards and three touchdowns throughout his five-year NFL career.

OCTOBER 28, 2023 • ROTOWIRE

Gets elevated for Thursday Buffalo elevated Isabella from its practice squad to the active roster for Thursday's game versus Tampa Bay.

Impact Isabella is in position to make his 2023 debut in Week 8 on Thursday Night Football. Barring an injury to Stefon Diggs or Gabe Davis though, his theoretical path to significant playing time is difficult to see.

OCTOBER 26, 2023 • ROTOWIRE

Former UMass star Andy Isabella helps pick up the pace for the Bills in a key AFC East showdown - The Boston Globe The practice squad receiver has been used this week to help simulate the speed of some of the Dolphins' key weapons.

SEPTEMBER 29, 2023 • BOSTONGLOBE.COM

Bills Plans for Andy Isabella? Buffalo Bills still believe WR Andy Isabella will help them this season

SEPTEMBER 2, 2023 • STAR-TELEGRAM.COM

Bills Plans for Andy Isabella? Buffalo Bills still believe WR Andy Isabella will help them this season

SEPTEMBER 2, 2023 • NEWSOBSERVER.COM

Can Andy Isabella be more than just a preseason darling for the Bills? Former UMass coach Mark Whipple wouldn't be surprised if the 2019 draft pick found a way to stick in Buffalo.

AUGUST 19, 2023 • THEATHLETIC.COM

Andy Isabella: "Play Hard Everyday" Bills Wide Receiver Andy Isabella addresses the media following Training Camp practice on Thursday, August 17th. Topics include: playing har...

AUGUST 17, 2023 • BUFFALOBILLS.COM

Andy Isabella outraces LB for 30-yard catch-and-run | Bills vs. Colts preseason Buffalo Bills wide receiver Andy Isabella outraces LB for 30-yard catch-and-run.

AUGUST 12, 2023 • BUFFALOBILLS.COM

Ravens release WRs Andy Isabella and Mike Thomas, claim WR Makai Polk off waivers

The Baltimore Ravens have released wide receivers Andy Isabella and Mike Thomas and claimed receiver Makai Polk off waivers

JULY 25, 2023 • Associated Press

Lands new contract with Baltimore The Ravens signed Isabella to a reserve/future contract Thursday, Field Yates of ESPN reports.

Impact Isabella will stick with Baltimore after joining the team's practice squad Oct. 10. The 5-foot-9 wideout collected 30 of 47 targets for 413 yards and three touchdowns over his first two seasons with Arizona, though he became a total non-factor in 2021 and was waived after the first four games of the 2022 regular season. Isabella was elevated for three games with Baltimore, including the loss to Cincinnati in the wild-card round of the playoffs. However, he never caught a pass while playing six offensive snaps across these contests, so he'll look to carve out a much more significant role heading into the 2023 campaign.

JANUARY 19, 2023 • ROTOWIRE

Reverts to practice squad Isabella reverted to Baltimore's practice squad Monday, per the NFL's transaction log.

Impact Isabella was elevated for a third (and final) time during the wild-card loss to Cincinnati but failed to log any counting stats across three offensive snaps. He made five appearances during the 2022 campaign (three with Arizona and two with Baltimore) and caught two of five targets for 21 yards, which all came as a Cardinal.

JANUARY 16, 2023 • ROTOWIRE

Jumps up from practice squad The Ravens elevated Isabella (thigh) from the practice squad to the active roster Saturday ahead of Sunday's wild-card game at Cincinnati, Ryan Mink of the team's official site rep...

Impact This marks Isabella's third (and final) elevation of the 2022 season and his first since injuring his thigh Week 17 versus the Steelers. Considering he's back on the active roster, the health concern is behind him, and with Tylan Wallace (hamstring) hitting IR on Saturday, Isabella could be more utilized on offense this weekend than in prior games, with Demarcus Robinson, Sammy Watkins, James Proche and fellow practice-squad call-up Binjimen Victor serving as Baltimore's other healthy wide receivers.

JANUARY 15, 2023 • ROTOWIRE

Ravens elevate WRs Andy Isabella, Binjimen Victor for playoff game vs. Bengals, sign DB Ar'Darius Washington to active roster Wide receivers Andy Isabella and Binjimen Victor have been elevated from practice squad, while wide receiver Tylan Wallace (hamstring) was p...

JANUARY 14, 2023 • BALTIMORESUN.COM

Shifts back to practice squad Isabella reverted to Baltimore's practice squad Monday, per the NFL's official transaction log.

Impact Isabella was promoted to the active roster for the second time in as many weeks ahead of Sunday's loss to Pittsburgh. He wound up logging a one-yard rush while playing three of his six snaps on offense, and he was forced out with a thigh during the third quarter. It's unclear if this issue will affect his availability for the Ravens' regular-season finale, but he should still be considered a top candidate for a depth role in the team's undermanned receiving corps when healthy.

JANUARY 2, 2023 • ROTOWIRE

Injures thigh Sunday Isabella suffered a thigh injury during Sunday's game against the Steelers.

Impact Prior to his exit in the third quarter, Isabella had one carry for one yard. The Ravens elevated him from the practice squad for Week 17 action, so he'll revert back for a second consecutive week Monday.

JANUARY 2, 2023 • ROTOWIRE

Elevated to active roster The Ravens elevated Isabella from their practice squad to the active roster Saturday ahead of the Week 17 contest against the Steelers, Field Yates of ESPN reports.

Impact This marks Isabella's second straight elevation for Baltimore, as he played three offensive snaps and five special-teams snaps last week against Atlanta. The fourth-year wideout also played in three games for the Cardinals earlier this season, catching two passes on five targets for 21 yards. The Ravens' passing game has been fairly unproductive of late with Tyler Huntley -- who will start Sunday against Pittsburgh -- at the helm in place of Lamar Jackson (knee).

JANUARY 1, 2023 • ROTOWIRE

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Ravens release WRs Andy Isabella and Mike Thomas, claim WR Makai Polk off waivers