Lions vs. Bears 2025 Prediction, Odds, Picks - Sep 14

Lions vs. Bears 2025 Prediction, Odds, Picks - Sep 14

Updated Sep. 14, 2025 12:43 p.m. ET
Data Skrive

The Detroit Lions (0-1) and Chicago Bears (0-1) will play each other in a matchup of two division rivals. The Lions are the favorites, expected to win by at least a field goal but less than a touchdown (currently -6). The game has an over/under of 46.5 points.

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Lions vs. Bears Odds & Betting Lines

Lions vs Bears Betting Information updated as of September 14, 2025, 11:33 a.m. ET.
Favorite Spread Favorite Spread Odds Underdog Spread Odds Total Over Total Odds Under Total Odds
Lions -6 -108 -112 46.5 -108 -112

Lions vs. Bears Prediction & Pick

  • Pick ATS: Lions (-6)
  • Pick OU: Over (46.5)
  • Prediction: Lions 35 - Bears 12

How to Watch Detroit vs. Chicago

Lions vs. Bears Recent Matchups

  • Over their last five meetings, Detroit has tallied four wins against Chicago.
  • In their last five head-to-head matchups, Detroit has tallied 142 points versus Chicago, while allowing only 101 points.

Detroit Betting Info

  • Detroit compiled a 12-4-1 ATS record last year.
  • Against the spread, as 6-point favorites or more, the Lions went 4-2 last year.
  • Last season, the combined scoring went over the point total nine times in Detroit games.
  • The Lions were the moneyline favorite 16 total times last season. They finished 14-2 in those games.
  • Detroit went 5-1 last year (winning 83.3% of its games) when it played as a moneyline favorite of -270 or shorter.
  • Based on this matchup's moneyline, the Lions' implied win probability is 73.0%.

Lions Stats (2024)

Stat Average (Total) Rank
Pass yards 263.2 (4,474) 2
Rush yards 146.4 (2,488) 6
Points scored 33.2 (564) 1
Pass yards against 244.0 (4,148) 30
Rush yards against 98.4 (1,672) 5
Points allowed 20.1 (342) 7

Detroit's Key Players

Offense

  • Over the course of 17 games played last year, Jared Goff totaled 4,629 passing yards (second-best in the NFL), while throwing 37 touchdowns (fourth in the NFL) against 12 interceptions and completing 72.4% of his passes.
  • Jahmyr Gibbs scored 16 rushing touchdowns, while totaling 1,412 rushing yards (5.6 per carry and 83.1 per game).
  • Gibbs also had 52 catches for 517 yards with four receiving touchdowns. He was targeted 63 times and averaged 30.4 yards per game.
  • In 17 games played last season, Amon-Ra St. Brown had 115 catches (6.8 receptions per game on 8.3 targets per game) for 1,263 yards (fifth in the NFL) and 12 receiving touchdowns (third in the NFL).
  • David Montgomery had 775 rushing yards and 12 rushing touchdowns, while averaging 55.4 yards per game and 4.2 per attempt (27th in the NFL).
  • Montgomery also had 341 receiving yards (24.4 per game) on 36 catches (2.6 per game). He was targeted 38 times while he is still seeking his first receiving touchdown.

Defense

  • Brian Branch had 1.0 sack to go with 8.0 TFL, 109 tackles, and four interceptions over 16 games in 2024.
  • Jack Campbell had 1.5 sacks in addition to his 5.0 TFL and 125 tackles over 17 games.
  • Kerby Joseph had 1.0 TFL, 82 tackles, and nine interceptions.
  • D.J. Reed Jr. had 1.0 sack to go with 4.0 TFL and 64 tackles over 14 games for the Jets.

Chicago Betting Info

  • Chicago covered eight times in 17 games with a spread last year.
  • As 6-point underdogs or more, the Bears went 3-2-1 against the spread last year.
  • Chicago games hit the over seven out of 17 times last season.
  • The Bears won two, or 15.4%, of the 13 games they played as underdogs last season.
  • Chicago was 1-3 last season when entering a game as the underdog by +220 or more on the moneyline.
  • The bookmakers' moneyline implies a 31.2% chance of a victory for the Bears.

Bears Stats (2024)

Stat Average (Total) Rank
Pass yards 181.5 (3,086) 31
Rush yards 102.0 (1,734) 25
Points scored 18.2 (310) 28
Pass yards against 217.9 (3,705) 16
Rush yards against 136.3 (2,317) 28
Points allowed 21.8 (370) 13

Chicago's Key Players

Offense

  • In 17 games last year, Caleb Williams totaled 3,541 passing yards, while throwing 20 TD passes and six INTs, connecting on 62.5% of his attempts.
  • He added 489 yards on the ground, with zero rushing TDs. He averaged 28.8 yards per game and 6.0 per attempt.
  • D'Andre Swift averaged 56.4 rushing yards in 17 games (959 total yards), and scored six rushing TDs.
  • Swift also had 42 catches for 386 yards. He was targeted 52 times and averaged 22.7 yards per game.
  • Last season, D.J. Moore caught 98 passes for 966 yards and six TDs . He was targeted 140 times, and averaged 5.8 receptions in 17 games.
  • Rome Odunze had 54 receptions for 734 yards and three TDs. He averaged 3.2 yards per game in 17 games and was targeted 101 times.

Defense

  • T.J. Edwards had 4.0 sacks to go along with 12.0 TFL, 129 tackles, and one interception in his 17 games in 2024.
  • Kevin Byard had 2.0 sacks plus 5.0 TFL, 130 tackles, and one interception.
  • Tremaine Edmunds had 1.0 sack and 3.0 TFL, 110 tackles, and one interception during the 2024 campaign.
  • Tyrique Stevenson's stats for the year included 75 tackles, 1.0 TFL, and two interceptions over 16 games.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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