49ers vs. Bears Injury Report – Week 17, 2025

The San Francisco 49ers (11-4) have nine players on the injury report, including Christian McCaffrey, ahead of their matchup versus the Chicago Bears (11-4) at Levi's Stadium, on Sunday, Dec. 28 at 8:20 p.m. ET.

Learn more about the San Francisco 49ers vs. the Chicago Bears on FOX Sports!

49ers vs. Bears Game Info

• When: Sunday, December 28, 2025 at 8:20 p.m. ET
• Where: Levi's Stadium in Santa Clara, California
• TV info: NBC/Peacock
• Spread Favorite: 49ers (-3.5)
• Moneyline: 49ers (-185), Bears (+154)
• Total: 51.5 points
• Live Boxscore: FOX Sports

49ers Injuries

Renardo Green | CB (Out)

• Injury: Neck
• Practice Status: Limited Participation in Practice
• 2025 Defensive Stats: 0.0 Sacks | 0.0 Tackles for Loss | 52 Tackles | 0 Interceptions | 9 Passes Defended

Kurtis Rourke | QB (Out)

• Injury: Knee
• Practice Status: Full Participation in Practice

Ricky Pearsall | WR (Questionable)

• Injury: Knee
• Practice Status: Limited Participation in Practice
• 2025 Receiving Stats: 45 Targets | 31 Receptions | 443 Yards | 0 Touchdowns

George Kittle | TE (Questionable)

• Injury: Ankle
• Practice Status: Did Not Participate In Practice
• 2025 Receiving Stats: 62 Targets | 52 Receptions | 599 Yards | 7 Touchdowns

Sam Okuayinonu | DL

• Injury: Ankle
• Practice Status: Full Participation in Practice
• 2025 Defensive Stats: 2.0 Sacks | 3.0 Tackles for Loss | 34 Tackles | 0 Interceptions | 0 Passes Defended

Christian McCaffrey | RB

• Injury: Rest
• Practice Status: Full Participation in Practice
• 2025 Rushing: 280 Attempts | 1,039 Yards | 9 Touchdowns
• 2025 Receiving Stats: 116 Targets | 92 Receptions | 849 Yards | 7 Touchdowns

Yetur Gross-Matos | DL

• Injury: Knee
• Practice Status: Limited Participation in Practice

Tatum Bethune | LB

• Injury: Ankle
• Practice Status: Full Participation in Practice
• 2025 Defensive Stats: 0.0 Sacks | 2.0 Tackles for Loss | 73 Tackles | 0 Interceptions | 2 Passes Defended

Trent Williams | OT

• Injury: Rest
• Practice Status: Full Participation in Practice
• 2025 Season Stats: 5 Games Played

Bears Injuries

Nick McCloud | CB (Out)

• Injury: Illness
• Practice Status: Did Not Participate In Practice
• 2025 Defensive Stats: 0.0 Sacks | 0.0 Tackles for Loss | 26 Tackles | 0 Interceptions | 2 Passes Defended

Rome Odunze | WR (Out)

• Injury: Foot
• Practice Status: Did Not Participate In Practice
• 2025 Receiving Stats: 90 Targets | 44 Receptions | 661 Yards | 6 Touchdowns

D.J. Moore | WR (Questionable)

• Injury: Illness
• Practice Status: Full Participation in Practice
• 2025 Receiving Stats: 78 Targets | 48 Receptions | 664 Yards | 6 Touchdowns

Luke Newman | OL (Questionable)

• Injury: Foot
• Practice Status: Full Participation in Practice

C.J. Gardner-Johnson | S (Questionable)

• Injury: Knee
• Practice Status: Full Participation in Practice
• 2025 Defensive Stats: 3.0 Sacks | 5.0 Tackles for Loss | 55 Tackles | 2 Interceptions | 3 Passes Defended

Nahshon Wright | CB (Questionable)

• Injury: Hamstring
• Practice Status: Did Not Participate In Practice
• 2025 Defensive Stats: 0.0 Sacks | 3.0 Tackles for Loss | 67 Tackles | 5 Interceptions | 12 Passes Defended

Josh Blackwell | DB (Questionable)

• Injury: Illness
• Practice Status: Did Not Participate In Practice
• 2025 Season Stats: 11 Games Played

Olamide Zaccheaus | WR (Questionable)

• Injury: Illness
• Practice Status: Full Participation in Practice
• 2025 Receiving Stats: 65 Targets | 39 Receptions | 313 Yards | 2 Touchdowns

T.J. Edwards | LB (Questionable)

• Injury: Glute
• Practice Status: Limited Participation in Practice
• 2025 Defensive Stats: 0.5 Sacks | 2.0 Tackles for Loss | 54 Tackles | 0 Interceptions | 3 Passes Defended

Travis Homer | RB

• Injury: Ankle
• Practice Status: Full Participation in Practice
• 2025 Season Stats: 6 Games Played

Devin Duvernay | WR

• Injury: Illness
• Practice Status: Full Participation in Practice
• 2025 Season Stats: 15 Games Played

D'Marco Jackson | LB

• Injury: Illness
• Practice Status: Full Participation in Practice
• 2025 Defensive Stats: 1.0 Sack | 2.0 Tackles for Loss | 33 Tackles | 1 Interception | 3 Passes Defended

Drew Dalman | OL

• Injury: Ankle
• Practice Status: Full Participation in Practice
• 2025 Season Stats: 3 Games Played

Kevin Byard | DB

• Injury: Ankle
• Practice Status: Full Participation in Practice
• 2025 Defensive Stats: 0.0 Sacks | 4.0 Tackles for Loss | 83 Tackles | 6 Interceptions | 7 Passes Defended

Luther Burden III | WR

• Injury: Ankle
• Practice Status: Full Participation in Practice

Joe Thuney | OG

• Injury: Nir - rest
• Practice Status: Full Participation in Practice
• 2025 Season Stats: 2 Games Played

Amen Ogbongbemiga | LB

• Injury: Hamstring
• Practice Status: Full Participation in Practice
• 2025 Defensive Stats: 0.0 Sacks | 0.0 Tackles for Loss | 16 Tackles | 0 Interceptions | 1 Pass Defended

49ers vs. Bears Head-to-Head History

• Over their last five meetings, San Francisco has totaled three wins versus Chicago.
• In their last five head-to-head matchups, San Francisco has racked up 105 points against Chicago, while giving up only 82 points.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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