Twins vs. Nationals Prediction, Odds, Picks - July 25

Byron Buxton and James Wood will be among the stars on display when the Minnesota Twins play the Washington Nationals on Friday at 8:10 p.m. ET, at Target Field. Oddsmakers list the Twins as -229 favorites on the moneyline, while giving the underdog Nationals +188 moneyline odds. Minnesota is a 1.5-run favorite (at -113 odds). The total for the matchup is set at 8.5 runs.

Here's everything you need to know from a betting perspective on the Twins-Nationals game, regarding the run line, moneyline and total, plus expert picks.

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Twins vs. Nationals Game Information & Odds

• When: Friday, July 25, 2025 at 8:10 p.m. ET
• Where: Target Field in Minneapolis, Minnesota
• How to watch on TV: MLB Network, MNNT, and MASN2

Twins vs. Nationals Prediction

• Score Prediction: Twins 5, Nationals 4
• Total Prediction: Over 8.5 runs
• Win Probabilities: Twins 56%, Nationals 44%

Twins vs. Nationals Betting Insights

• The Twins have entered the game as favorites 65 times this season and won 34, or 52.3%, of those games.
• Minnesota has entered three games this season favored by -229 or more, and won each of those games.
• The implied probability of a win from the Twins, based on the moneyline, is 69.6%.
• The Nationals have won in 37, or 43%, of the 86 contests they have been named as odds-on underdogs this year.
• This season, Washington has been victorious three times in 10 chances when named as an underdog of at least +188 or longer on the moneyline.
• The Nationals have an implied victory probability of 34.7% according to the moneyline set by oddsmakers for this matchup.

Twins Recent Betting Performance

• The Twins have a 3-3 record across the six games they were favored on the moneyline in their last 10 matchups.
• In their last 10 outings (all had set totals), the Twins combined with their opponents to hit the over on the total three times.
• The Twins' ATS record is 4-6-0 over their past 10 games.

Twins Recent Stats

Twins Player Insights

• Buxton is the bat to watch in the Twins lineup, leading the team in batting average (.288), home runs (23), and RBI (58).
• Among all hitters in baseball, Buxton's home run total places him 12th, and his RBI tally ranks him 34th.
• Trevor Larnach is batting .245 with 15 doubles, a triple, 13 home runs and 34 walks.
• Larnach is 85th in homers and 95th in RBI among all major league hitters this year.
• Ty France is hitting .249 with 18 doubles, six home runs and 17 walks.
• France will look to build on his two-game hitting in this game. In his last five games he is batting .235 with two doubles, two walks and an RBI.
• Carlos Correa is hitting .266 with 19 doubles, seven home runs and 25 walks.

Twins Team Props

Nationals Recent Betting Performance

• The Nationals have played as underdogs in 10 of their past 10 games and have gone 3-7 in those contests.
• In their last 10 games with a total, the Nationals and their opponents have combined to hit the over six times.
• The Nationals have four wins against the spread in their last 10 chances.

Nationals Recent Stats

Nationals Player Insights

• Wood leads the Nationals in home runs (24) and runs batted in (70).
• Wood's home run total places him 10th in the majors, and he is 12th in RBI.
• C.J. Abrams' .276 batting average is a team-high mark.
• Abrams ranks 85th among all hitters in MLB in homers, and 142nd in RBI.
• Luis Garcia is hitting .261 with 20 doubles, seven home runs and 20 walks.
• Nathaniel Lowe has 15 doubles, two triples, 15 home runs and 37 walks while batting .226.

Nationals Team Props

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FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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