Cubs vs. Reds Prediction, Odds, Picks - May 23

The Cincinnati Reds and Will Benson hit the field against Kyle Tucker and the Chicago Cubs on Friday at Great American Ball Park. The favored Cubs have -115 moneyline odds to win against the underdog Reds, who are listed at -104. Chicago is a 1.5-run favorite (at +145 odds). An 8.5-run over/under is set in the matchup.

Take a look at everything you need from a betting perspective on the Cubs-Reds game, regarding the run line, moneyline and total, plus expert picks.

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Cubs' Kyle Tucker smacks a solo homer as Cubs strike first vs. Marlins

The Chicago Cubs' Kyle Tucker smacked a solo homer as the Chicago Cubs struck first vs. the Marlins.

Cubs vs. Reds Game Information & Odds

• When: Friday, May 23, 2025 at 6:40 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and MARQ

Cubs vs. Reds Prediction

• Score Prediction: Cubs 5, Reds 4
• Total Prediction: Under 8.5 runs
• Win Probabilities: Cubs 52%, Reds 48%

Cubs vs. Reds Betting Insights

• The Cubs have entered the game as favorites 31 times this season and won 21, or 67.7%, of those games.
• This season Chicago has won 21 of its 31 games, or 67.7%, when favored by at least -115 on the moneyline.
• The bookmakers' moneyline implies a 53.5% chance of a victory for the Cubs.
• The Reds have been victorious in 12, or 48%, of the 25 contests they have been chosen as underdogs in this season.
• Cincinnati has a win-loss record of 11-12 when favored by -104 or worse by bookmakers this year.
• The Reds have an implied victory probability of 51% according to the moneyline set by sportsbooks for this matchup.

Cubs Recent Betting Performance

• The Cubs went 7-2 across the nine games they were moneyline favorites in their last 10 matchups.
• In their last 10 matchups (all had set totals), the Cubs combined with their opponents to hit the over on the total five times.
• The Cubs have a 5-5-0 record against the spread over their past 10 games.

Cubs Recent Stats

Cubs Player Insights

• Tucker leads the Cubs with 12 big flies on the year. He's also hitting .278 with 35 RBI.
• In all of MLB, Tucker ranks ninth in home runs and 12th in RBI.
• Tucker has collected a hit in two straight games. In his last five games he is batting .389 with two home runs, five walks and two RBIs.
• Pete Crow-Armstrong's 12 home runs lead his team.
• Crow-Armstrong ranks ninth in home runs and fifth in RBI among all hitters in baseball.
• Seiya Suzuki has accumulated a team-high 12 home runs and 43 runs batted in.
• Suzuki has at least one base hit in three games in a row. During his last five outings he is hitting .316 with two doubles, a home run, three walks and six RBIs.
• Dansby Swanson is hitting .262 with seven doubles, a triple, 10 home runs and 17 walks.
• Swanson is riding a seven-game hitting streak into this one. During his last 10 outings he is batting .351 with two home runs, four walks and five RBIs.

Cubs Team Props

Reds Recent Betting Performance

• The Reds have played as underdogs in three of their past 10 games and have gone 2-1 in those contests.
• Games involving the Reds have not hit the over in 10 straight contests with a total.
• The Reds have five wins against the spread in their last 10 chances.

Reds Recent Stats

Reds Player Insights

• Elly De La Cruz has a team-high eight home runs and has driven in 33 runs.
• In all of the big leagues, De La Cruz is 47th in homers and 19th in RBI.
• TJ Friedl has eight doubles, two triples, three home runs and 23 walks while batting .274.
• Friedl ranks 180th overall in homers and 134th in RBI this year.
• Gavin Lux has accumulated a team-high batting average of .292.
• Austin Hays is hitting .316 with six doubles, six home runs and seven walks.

Reds Team Props

Reds vs. Pirates Highlights | MLB on FOX

Check out the best moments between the Cincinnati Reds and the Pittsburgh Pirates.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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