Motherwell will be without the services of Michael Higdon and Stephen Craigan for the game.
Higdon was handed a one-match suspension for making an apparent gesture when celebrating his goal in Saturday's draw with Dundee United, while Craigan was ordered-off in the midweek victory over Dunfermline.
Defender Steven Saunders (Achilles) remains out, while reserve goalkeeper Lee Hollis has made an initial return to training after a hip injury.
Frazer Wright and Chris Millar are back in contention for St Johnstone.
Wright has not played since December 3 when he tore his thigh muscle in a game against Hearts at Tynecastle.
Millar, meanwhile, injured a hamstring in the December 28 meeting against Kilmarnock at McDiarmid Park.
Motherwell (from): Randolph, Hateley, Hammell, Hutchinson, Lasley, Law, Daley, Murphy, Humphrey, Forbes, Page, McHugh, Clancy, Bradley, Pollock, Ojamaa, Jennings, Carswell.
St Johnstone (from): Enckelman, MacKay, Anderson, Wright, McCracken, Callum Davidson, Croft, Compton, Morris, Millar, Murray Davidson, Craig, Sandaza, Haber, Sheridan, Mannus, Maybury, Moffat, Stewart, Gray.
